Hypertension is a complex genetic disorder caused by interplay between several 'risk'genes
and environmental factors (genetic heritability∼ 30%). Most genetic studies of hypertension …

We conducted a systematic review by searching the Medline literature from March 1993 to
June 2003. Each paper was scrutinized and data concerning study population, method of …

We analyzed the association between salt sensitivity in essential hypertension and 8 genetic
polymorphisms in 6 genes of the renin-angiotensin aldosterone system. Seventy-one …

Background The genes encoding angiotensin converting enzyme (ACE, I/D), α-adducin
(ADD, Gly460Trp) and aldosterone synthase (AS,− 344C/T) share the potential of …

The objective of this study was to determine whether racial or ethnic differences in
prevalence of diabetic microalbuminuria were observed in a large primary care population …

Background The CYP11B2 gene (CYP11B2) encoding aldosterone synthase has been
associated with essential hypertension and some, but not all, studies have reported that the …

Background The aldosterone synthase gene (CYP1B2) locus is a candidate region involved
in the development of hypertension. Objective To study the relationship between the C-344T …

Background: Human hypertension is a complex, multifactorial disease with a heritability of
more than 30–50%. A genetic screening test based on analysis of multiple single-nucleotide …

Objective The CYP11B2 locus is an important candidate region in essential hypertension
(HT). We therefore investigated CYP11B2 polymorphisms T− 344C, T4986C and A6547G …

Functional angiotensin II receptors have been documented in cardiac fibroblasts as well as
an intracardiac aldosterone system that responds to short-and long-term physiological …