Unravelling the immunobiology of innate lymphoid cells (ILCs): Implications in health and disease
Innate lymphoid cells (ILCs), a growing class of immune cells, imitate the appearance and
abilities of T cells. However, unlike T cells, ILCs lack acquired antigen receptors, and they …
abilities of T cells. However, unlike T cells, ILCs lack acquired antigen receptors, and they …
Lymphocyte homing and recirculation with tumor tertiary lymphoid structure formation: predictions for successful cancer immunotherapy
W Tian, W Wei, G Qin, X Bao, X Tong, M Zhou… - Frontiers in …, 2024 - frontiersin.org
The capacity of lymphocytes continuously home to lymphoid structures is remarkable for
cancer immunosurveillance and immunotherapy. Lymphocyte homing and recirculation …
cancer immunosurveillance and immunotherapy. Lymphocyte homing and recirculation …
Distinct ontogenetic lineages dictate cDC2 heterogeneity
CM Minutti, C Piot, M Pereira da Costa… - Nature …, 2024 - nature.com
Conventional dendritic cells (cDCs) include functionally and phenotypically diverse
populations, such as cDC1s and cDC2s. The latter population has been variously …
populations, such as cDC1s and cDC2s. The latter population has been variously …
Chemo‐and mechanosensing by dendritic cells facilitate antigen surveillance in the spleen
Spleen dendritic cells (DC) are critical for initiation of adaptive immune responses against
blood‐borne invaders. Key to DC function is their positioning at sites of pathogen entry, and …
blood‐borne invaders. Key to DC function is their positioning at sites of pathogen entry, and …
Redefining the role of lymphotoxin beta receptor in the maintenance of lymphoid organs and immune cell homeostasis in adulthood
Y Shou, E Koroleva, CM Spencer, SA Shein… - Frontiers in …, 2021 - frontiersin.org
Lymphotoxin beta receptor (LTβR) is a promising therapeutic target in autoimmune and
infectious diseases as well as cancer. Mice with genetic inactivation of LTβR display multiple …
infectious diseases as well as cancer. Mice with genetic inactivation of LTβR display multiple …
Reciprocal costimulatory molecules control the activation of mucosal type 3 innate lymphoid cells during engagement with B cells
X Lv, S Zhu, J Wu, J Shi, Q Wei, T Li, N Yang… - Cellular & Molecular …, 2023 - nature.com
Innate lymphoid cells (ILCs) are the counterpart of T helper cells in the innate immune
system and share multiple phenotypes with T helper cells. Inducible T-cell costimulator …
system and share multiple phenotypes with T helper cells. Inducible T-cell costimulator …
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation
VS Gogoleva, MS Drutskaya… - European Journal of …, 2024 - Wiley Online Library
Lymphotoxin α and lymphotoxin β (LTs), TNF superfamily members, are expressed in either
soluble (LTα3) or membrane‐bound (LTα1β2 or LTα2β1) forms. In the pathological context …
soluble (LTα3) or membrane‐bound (LTα1β2 or LTα2β1) forms. In the pathological context …
多发性硬化三级淋巴结构的研究进展
刘双， 马坚妹 - 解剖学报, 2024 - jpxb.bjmu.edu.cn
多发性硬化(multiplesclerosis, MS) 是一种中枢神经系统自身免疫性疾病, 其病理变化主要包括
淋巴细胞浸润, 胶质细胞活化, 髓鞘脱失和神经退行变等. 随着MS 进展, 外周浸润的免疫细胞 …
淋巴细胞浸润, 胶质细胞活化, 髓鞘脱失和神经退行变等. 随着MS 进展, 外周浸润的免疫细胞 …
Lymphotoxins Serve as a Novel Orchestrator in T1D Pathogenesis
SW Liu, F Sun, SJ Rong, T Wang, CY Wang - Frontiers in Immunology, 2022 - frontiersin.org
Type 1 diabetes (T1D) stems from pancreatic β cell destruction by islet reactive immune
cells. Similar as other autoimmune disorders, there is no curative remedy for T1D thus far …
cells. Similar as other autoimmune disorders, there is no curative remedy for T1D thus far …
Research progress of the tertiary lymphoid structure in multiple sclerosis
LIUSMA Jian-mei - Acta Anatomica Sinica, 2024 - jpxb.bjmu.edu.cn
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS), which is characterized by infiltration of immune cells, glia activation, demyelination …
(CNS), which is characterized by infiltration of immune cells, glia activation, demyelination …