Chemistry and biology of multicomponent reactions
Multicomponent reactions (MCRs) are one-pot reactions employing more than two starting
materials, for example, 3, 4,..., 7, where most of the atoms of the starting materials are …
materials, for example, 3, 4,..., 7, where most of the atoms of the starting materials are …
Metal-free multicomponent syntheses of pyridines
C Allais, JM Grassot, J Rodriguez… - Chemical …, 2014 - ACS Publications
They react according to a succession of mono-or bimolecular processes to form at the end
one product that incorporates important portions and functionalities of the starting materials …
one product that incorporates important portions and functionalities of the starting materials …
Recent applications of multicomponent reactions in medicinal chemistry
Multicomponent reactions are flexible reactions for the rapid generation of complex
molecules with often biologically relevant scaffold structures. Combined with the ease of …
molecules with often biologically relevant scaffold structures. Combined with the ease of …
Imidazo[1,2-a]pyridines Susceptible to Excited State Intramolecular Proton Transfer: One-Pot Synthesis via an Ortoleva–King Reaction
AJ Stasyuk, M Banasiewicz, MK Cyrański… - The Journal of organic …, 2012 - ACS Publications
A short and efficient route to a broad range of imidazo [1, 2-a] pyridines from 2-
aminopyridines and acetophenones is achieved by a tandem, one-pot process starting with …
aminopyridines and acetophenones is achieved by a tandem, one-pot process starting with …
The Groebke‐Blackburn‐Bienaymé Reaction
A Boltjes, A Dömling - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …
Pyrimidazole-based covalent organic frameworks: integrating functionality and ultrastability via isocyanide chemistry
J Liu, T Yang, ZP Wang, PL Wang, J Feng… - Journal of the …, 2020 - ACS Publications
Development of new chemistry to simultaneously meet the demands for topology,
connectivity, and functionality is highly desired in the research area of covalent organic …
connectivity, and functionality is highly desired in the research area of covalent organic …
Imidazo [1, 2-a] pyridine scaffold as prospective therapeutic agents
Imidazo [1, 2-a] pyridine is one of the most potential bicyclic 5–6 heterocyclic rings that is
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
recognized as a “drug prejudice” scaffold due to its broad range of applications in medicinal …
Diversity-oriented synthesis of fused-imidazole derivatives via Groebke–Blackburn–Bienayme reaction: a review
In recent time, diversity-oriented synthesis of small chemical entities has been emerged as a
possible tool for exploring the intersections between chemistry and biology. These small …
possible tool for exploring the intersections between chemistry and biology. These small …
Medicinal attributes of imidazo [1, 2-a] pyridine derivatives: an update
The imidazo [1, 2-a] pyridine scaffold is recognized as a privileged structure as it represents
a promising area for identification of lead structures towards the discovery of new synthetic …
a promising area for identification of lead structures towards the discovery of new synthetic …
Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review
J Panda, BP Raiguru, M Mishra, S Mohapatra… - …, 2022 - Wiley Online Library
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …