Galaxy masses

S Courteau, M Cappellari, RS de Jong, AA Dutton… - Reviews of Modern …, 2014 - APS
Galaxy masses play a fundamental role in our understanding of structure formation models.
This review addresses the variety and reliability of mass estimators that pertain to stars, gas …

[HTML][HTML] Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

P Cimermancic, MH Medema, J Claesen, K Kurita… - Cell, 2014 - cell.com
Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …

Genomics and evolution of protein phosphatases

MJ Chen, JE Dixon, G Manning - Science signaling, 2017 - science.org
Protein phosphatases are the essential opposite to protein kinases; together, these enzymes
regulate all protein phosphorylation and most cellular processes. To better understand the …

Structure and function of lipid A–modifying enzymes

A Anandan, A Vrielink - Annals of the New York Academy of …, 2020 - Wiley Online Library
Lipopolysaccharides are complex molecules found in the cell envelop of many Gram‐
negative bacteria. The toxic activity of these molecules has led to the terminology of …

Insights into the assembly and activation of the microtubule nucleator γ-TuRC

P Liu, E Zupa, A Neuner, A Böhler, J Loerke… - Nature, 2020 - nature.com
Microtubules are dynamic polymers of α-and β-tubulin and have crucial roles in cell
signalling, cell migration, intracellular transport and chromosome segregation. They …

PROMALS3D: multiple protein sequence alignment enhanced with evolutionary and three-dimensional structural information

J Pei, NV Grishin - Multiple Sequence Alignment Methods, 2014 - Springer
Multiple sequence alignment (MSA) is an essential tool with many applications in
bioinformatics and computational biology. Accurate MSA construction for divergent proteins …

[HTML][HTML] A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis

MH Medema, P Cimermancic, A Sali… - PLoS computational …, 2014 - journals.plos.org
Bacterial secondary metabolites are widely used as antibiotics, anticancer drugs,
insecticides and food additives. Attempts to engineer their biosynthetic gene clusters (BGCs) …

[HTML][HTML] Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences

JL Mendoza, A Schmidt, Q Li, E Nuvaga, T Barrett… - Cell, 2012 - cell.com
Misfolding of ΔF508 cystic fibrosis (CF) transmembrane conductance regulator (CFTR)
underlies pathology in most CF patients. F508 resides in the first nucleotide-binding domain …

Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and …

KH Chan, JFW Chan, H Tse, H Chen, CCY Lau… - Journal of Infection, 2013 - Elsevier
OBJECTIVES: A severe acute respiratory syndrome (SARS)-like disease due to a novel
betacoronavirus, human coronavirus EMC (HCoV-EMC), has emerged recently. HCoV-EMC …

[HTML][HTML] Structure of the catalytic core of the Integrator complex

MM Pfleiderer, WP Galej - Molecular cell, 2021 - cell.com
The Integrator is a specialized 3′ end-processing complex involved in cleavage and
transcription termination of a subset of nascent RNA polymerase II transcripts, including …