Introduction From a biopharmaceutical standpoint, the skin is recognized as an interesting
route for drug delivery. In general, small molecules are able to penetrate the stratum …

According to Quality by Design (QbD) concept, quality should be built into product/method
during pharmaceutical/analytical development. Usually, there are many input factors that …

Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

ABSTRACT Introduction: Quality by design (QbD) encourages the pharmaceutical industry
to use risk management and science-based manufacturing principles to gain process and …

Purpose The anticancer potential of indomethacin and other nonsteroidal anti-inflammatory
drugs (NSAIDs) in vitro, in vivo, and in clinical trials is well known and widely reported in the …

This research attempts to bring together the positive aspects of lipid nanoparticles and
Quality by Design (QbD) approach for developing a novel drug delivery system for skin …

As diabetes is a complex disorder being a major cause of mortality and morbidity in
epidemic rates, continuous research has been done on new drug types and administration …

Today, there is a rising demand and ongoing search for novel plant‐derived phytochemicals
in the cosmetic market owing to the growing consumer expectations worldwide for green …

Sorafenib (SRB), a multikinase inhibitor, is effective in reducing experimental corneal
neovascularization (CNV) after oral administration; however, its therapeutic use in ocular …

Ibrutinib (IBR) is the choice of drug for the treatment of chronic lymphocytic leukaemia (CLL)
and mantle cell lymphoma (MCL). IBR has low oral bioavailability of 2.9% owing to its high …