Antibiotic allergy

KG Blumenthal, JG Peter, JA Trubiano, EJ Phillips - The Lancet, 2019 - thelancet.com
Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …

Role of the pharmacist in reducing healthcare costs: current insights

K Dalton, S Byrne - Integrated Pharmacy Research and Practice, 2017 - Taylor & Francis
Global healthcare expenditure is escalating at an unsustainable rate. Money spent on
medicines and managing medication-related problems continues to grow. The high …

CSH guidelines for the diagnosis and treatment of drug-induced liver injury

Y Yu, Y Mao, C Chen, J Chen, J Chen, W Cong… - Hepatology …, 2017 - Springer
Drug-induced liver injury (DILI) is an important clinical problem, which has received more
attention in recent decades. It can be induced by small chemical molecules, biological …

Prevalence of adverse drug reactions in the primary care setting: A systematic review and meta-analysis

WN Insani, C Whittlesea, H Alwafi, KKC Man… - PLoS …, 2021 - journals.plos.org
Background Adverse drug reactions (ADRs) represent a major cause of iatrogenic morbidity
and mortality in patient care. While a substantial body of work has been undertaken to …

[图书][B] Lethal but legal: corporations, consumption, and protecting public health

N Freudenberg - 2014 - books.google.com
Decisions made by the food, tobacco, alcohol, pharmaceutical, gun, and automobile
industries have a greater impact on today's health than the decisions of scientists and …

HLA association with drug‐induced adverse reactions

WL Fan, MS Shiao, RCY Hui, SC Su… - Journal of …, 2017 - Wiley Online Library
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe
cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome …

Magnesium and drugs

U Gröber - International journal of molecular sciences, 2019 - mdpi.com
Several drugs including diuretics and proton-pump inhibitors can cause magnesium loss
and hypomagnesemia. Magnesium and drugs use the same transport and metabolism …

[HTML][HTML] Dissecting the molecular pathophysiology of drug-induced liver injury

H Ye, LJ Nelson, MG Del Moral… - World journal of …, 2018 - ncbi.nlm.nih.gov
Drug-induced liver injury (DILI) has become a major topic in the field of Hepatology and
Gastroenterology. DILI can be clinically divided into three phenotypes: hepatocytic …

Pharmacogenetics of drug–drug interaction and drug–drug–gene interaction: a systematic review on CYP2C9, CYP2C19 and CYP2D6

MA Bahar, D Setiawan, E Hak, B Wilffert - Pharmacogenomics, 2017 - Taylor & Francis
Currently, most guidelines on drug–drug interaction (DDI) neither consider the potential
effect of genetic polymorphism in the strength of the interaction nor do they account for the …

Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling

S Li, Y Yu, X Bian, L Yao, M Li, YR Lou, J Yuan… - Archives of …, 2021 - Springer
The risk of drug-induced liver injury (DILI) poses a major challenge for development of
natural products derived from traditional Chinese medicines (NP-TCMs). It is urgent to find a …