The localization of mRNAs to subcellular compartments provides a mechanism for
regulating gene expression with exquisite temporal and spatial control. Recent studies …

The cytoskeleton is an interconnected network that provides support and organization to
cells. In eukaryotes, its main components include actin and microtubules, two types of …

As highlighted by recent genome-wide analyses in diverse organisms and cell types,
subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish …

Eukaryotic genomes generate a heterogeneous ensemble of mRNAs and long noncoding
RNAs (lncRNAs). LncRNAs and mRNAs are both transcribed by Pol II and acquire 5′ caps …

The eukaryotic family of RNA-binding proteins termed PUF (Pumilio and FBF) is known for
its roles in cell division, differentiation and development. The best-characterized function of …

RNA localization is essential for regulating spatial translation, where RNAs are trafficked to
their target locations via various biological mechanisms. In this review, we discuss RNA …

Essentially all cells contain a variety of spatially restricted regions that are important for
carrying out specialized functions. Often, these regions contain specialized transcriptomes …

Abstract mRNAs encoding mitochondrial proteins are enriched in the vicinity of
mitochondria, presumably to facilitate protein transport. A possible mechanism for …

Long-distance transport of mRNAs is important in determining polarity in eukaryotes.
Molecular motors shuttle large ribonucleoprotein complexes (mRNPs) containing RNA …

Productive cell proliferation involves efficient and accurate splitting of the dividing cell into
two separate entities. This orderly process reflects coordination of diverse cytological events …