Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

Pulmonary hypertension (PH) due to left heart disease, classified as group 2 according to
the Dana Point 2008 classification, is believed to be the most common cause of PH and is …

Considerable evidence is available in support of an independent association between
obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease, which is …

Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is
fundamental to human health. Sleep-disordered breathing, which disrupts such temporal …

Disturbances in cardiovascular neural regulation, influencing both disease course and
survival, progress as heart failure worsens. Heart failure due to left ventricular systolic …

Human aging is a complex phenomenon characterized by a wide spectrum of biological
changes which impact on behavioral and social aspects. Age-related changes are …

Awareness of the importance of sleep-related disorders in patients with cardiovascular
diseases is growing. In particular, sleep-disordered breathing, short sleep time, and low …

Autonomic nervous system (ANS) has been extensively explored in obstructive sleep apnea
(OSA). Autonomic alterations in these patients have been described by means of several …

There are three major types of sleep-disordered breathing (SDB) with respect to prevalence
and health consequences, ie obstructive sleep apnoea syndrome (OSAS), Cheyne–Stokes …