Advances in understanding the disease process in β-thalassemia supported development of
various treatment strategies that resulted in improved survival. Improved survival, however …

Patients with sickle cell anemia (SCA) experience cerebral metabolic stress with an increase
in oxygen extraction fraction (OEF) to compensate for reduced oxygen carrying capacity due …

Multi‐factorial causes jeopardize brain integrity in β‐thalassaemia. Intracranial parenchymal
and vascular changes have been reported among young β‐thalassaemia patients but …

The thalassemias are the most common single gene disorder in the world. Nowadays, the
average life expectancy of patients in developed countries has increased significantly, while …

Silent brain lesions might be associated with overt cerebrovascular accident over time in
beta thalassemia major (BTM) and intermediate (BTI). Aspirin may be protective in these …

Objective: This study aimed to explore the burden of magnetic resonance imaging (MRI) of
cerebral small vessel disease (CSVD) in patients with thalassemia and related risk factors …

Background: Several factors, including increased platelet aggregation, decreased platelet
survival, decreased anti-thrombotic factors cause a hypercoagulable state in thalassemia …