The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

Fifteen recommendations and a therapeutic algorithm regarding the management of acute
respiratory distress syndrome (ARDS) at the early phase in adults are proposed. The Grade …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is associated
with poor clinical outcomes. Although the importance and impact of lung-protective …

Neural respiratory drive, ie, the activity of respiratory centres controlling breathing, is an
overlooked physiologic variable which affects the pathophysiology and the clinical outcome …

Respiratory drive, the intensity of the respiratory center's output, determines the effort
exerted in each breath. The increasing awareness of the adverse effects of both strong and …

Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

Rationale: High-flow nasal cannula (HFNC) and helmet noninvasive ventilation (NIV) are
used for the management of acute hypoxemic respiratory failure. Objectives: Physiological …

Rationale: Monitoring and controlling respiratory drive and effort may help to minimize lung
and diaphragm injury. Airway occlusion pressure (P0. 1) is a noninvasive measure of …

During assisted mechanical ventilation, spontaneous inspiratory effort can cause both lung
(patient self-inflicted lung injury [P-SILI]) and diaphragm injury. While clinicians are primarily …

This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2020. Other selected articles can be found online at https://www …