Resveratrol and other natural oligomeric stilbenoid compounds and their therapeutic applications

CG Duta-Bratu, GM Nitulescu, DP Mihai, OT Olaru - Plants, 2023 - mdpi.com
The use of natural compounds as an alternative to synthetic molecules has become a
significant subject of interest in recent decades. Stilbenoids are a group of phenolic …

Occurrence, bioavailability, anti-inflammatory, and anticancer effects of pterostilbene

WS Lin, JV Leland, CT Ho, MH Pan - Journal of agricultural and …, 2020 - ACS Publications
Supplementation with natural compounds found in fruits and vegetables has long been
associated with a reduced risk of several types of cancer. Pterostilbene is a natural …

[HTML][HTML] Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses

X Yan, L Meng, X Zhang, Z Deng, B Gao, Y Zhang… - Molecular Therapy, 2023 - cell.com
Ulcerative colitis (UC) is a chronic or relapsing inflammatory disease with limited therapeutic
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …

Comparative Study of the Antioxidant Capacity of Four Stilbenes Using ORAC, ABTS+, and FRAP Techniques

P Rodríguez-Bonilla, F Gandía-Herrero… - Food Analytical …, 2017 - Springer
Researchers use several different analytical techniques, such as ORAC, ABTS·+, or FRAP,
for measuring the antioxidant capacity of bioactive compounds. However, many authors do …

Pterostilbene: Mechanisms of its action as oncostatic agent in cell models and in vivo studies

Z Ma, X Zhang, L Xu, D Liu, S Di, W Li, J Zhang… - Pharmacological …, 2019 - Elsevier
Pterostilbene, a natural dimethylated analog of resveratrol, exerts pleiotropic anticancer
effects against a variety of cancer types. Due to the better lipophilic and oral absorption …

Pterostilbene attenuates early brain injury following subarachnoid hemorrhage via inhibition of the NLRP3 inflammasome and Nox2-related oxidative stress

H Liu, L Zhao, L Yue, B Wang, X Li, H Guo, Y Ma… - Molecular …, 2017 - Springer
Pterostilbene (PTE), one of the polyphenols present in plants such as blueberries and
grapes, has been suggested to have various effects, such as anti-oxidation, anti-apoptosis …

Neuroprotective and anti-inflammatory effects of pterostilbene metabolites in human neuroblastoma SH-SY5Y and RAW 264.7 macrophage cells

P Peñalver, S Zodio, R Lucas, MV de-Paz… - Journal of agricultural …, 2020 - ACS Publications
Oxidative stress is known to be a key factor in many neurodegenerative diseases.
Inflammation also plays a relevant role in a myriad of pathologies such as diabetes and …

Potent inhibition of HIV-1 replication in resting CD4 T cells by resveratrol and pterostilbene

CN Chan, B Trinité, DN Levy - Antimicrobial agents and …, 2017 - Am Soc Microbiol
ABSTRACT HIV-1 infection of resting CD4 T cells plays a crucial and numerically dominant
role during virus transmission at mucosal sites and during subsequent acute replication and …

Discovery of novel pterostilbene derivatives that might treat sepsis by attenuating oxidative stress and inflammation through modulation of MAPKs/NF-κB signaling …

M Fang, T Zou, X Yang, Z Zhang, P Cao, J Han, Y Duan… - Antioxidants, 2021 - mdpi.com
Sepsis remains one of the most common life-threatening illnesses that is characterized by a
systemic inflammatory response syndrome (SIRS) and usually arises following severe …

Pterostilbene-isothiocyanate impedes RANK/TRAF6 interaction to inhibit osteoclastogenesis, promoting osteogenesis in vitro and alleviating glucocorticoid induced …

V Kumar, S Haldar, S Ghosh, S Chauhan… - Biochemical …, 2022 - Elsevier
Prolonged glucocorticoid treatment often leads to glucocorticoid-induced osteoporosis
(GIOP), a common iatrogenic complication. This study has explored the anti-osteoporotic …