Abstract 'Enriched environments' are a key experimental paradigm to decipher how
interactions between genes and environment change the structure and function of the brain …

The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

Dysregulation of the corticotropin-releasing factor (CRF)–urocortin (UCN) system has been
implicated in stress-related psychopathologies such as depression and anxiety. It has been …

Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

Environmental enrichment (EE) increases levels of novelty and complexity, inducing
enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …

Corticotropin-releasing hormone (CRH) is a central integrator in the brain of endocrine and
behavioral stress responses, whereas activation of the endocannabinoid CB1 receptor …

The etiology and pathophysiology of anxiety and mood disorders is linked to inappropriate
regulation of the central stress response. To determine whether microRNAs have a …

Social behavior in mammals is often studied in pairs under artificial conditions, yet groups
may rely on more complicated social structures. Here, we use a novel system for tracking …

Environmental enrichment (EE) has been shown to have powerful beneficial effects on a
variety of physiological and pathological processes. Accumulating evidence indicates that …

Background: Dysregulated stress neurocircuits, caused by genetic and/or environmental
changes, underlie the development of many neuropsychiatric disorders. Corticotropin …