Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …

Detection of mismatched human leukocyte antigens by adaptive immune cells is considered
as the main cause of transplant rejection, leading to either T-cell mediated rejection or …

Natural killer (NK) cells are part of the cellular immune response. They target mainly cancer
and virally infected cells. To a high extent cytotoxic activity of NK cells is regulated inter alia …

Abstract The XVI-th Banff Meeting for Allograft Pathology was held at Banff, Alberta, Canada,
from 19th to 23rd September 2022, as a joint meeting with the Canadian Society of …

Rejection remains the main cause of premature graft loss after kidney transplantation,
despite the use of potent immunosuppression. This highlights the need to better understand …

We studied the clinical, histologic, and molecular features distinguishing DSA-negative from
DSA-positive molecularly defined antibody-mediated rejection (mABMR). We analyzed …

Abstract Although anti–HLA (Human Leukocyte Antigen) donor-specific antibodies (DSAs)
are commonly measured in clinical practice and their relationship with transplant outcome is …

The activation of host's innate and adaptive immune systems can lead to acute and chronic
graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to …

Abstract Antibody-mediated rejection (AMR), including chronic AMR (cAMR), causes~ 50%
of kidney allograft losses each year. Despite attempts to develop well-tolerated and effective …

This review describes the development of the Molecular Microscope Diagnostic System
(MMDx) for heart transplant endomyocardial biopsies (EMBs). MMDx-Heart uses …