New information regarding neuronal circuits that control food intake and their hormonal
regulation has extended our understanding of energy homeostasis, the process whereby …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

The melanocortin system refers to a set of hormonal, neuropeptidergic, and paracrine
signaling pathways that are defined by components that include the five G protein-coupled …

Context Energy balance is critical for survival and health, and control of food intake is an
integral part of this process. This report reviews hormonal signals that influence food intake …

Obesity represents the most prevalent nutritional problem worldwide which in the long run
predisposes to development of diabetes mellitus, hypertension, endometrial carcinoma …

A method of treating patients for compulsive overeating includes stimulating left and right
branches of the patient's vagus nerve simultaneously with electrical pulses in a …

Numerous peripheral signals contribute to the regulation of food intake and energy
homeostasis. Mechano-and chemoreceptors signaling the presence and energy density of …

The homeostatic regulation of adiposity is a physiological concept that originated nearly 70
years ago, the genetic foundations of which have just begun to emerge. A key element of …

Body weight is regulated by complex neurohormonal interactions between endocrine
signals of long-term adiposity (eg, leptin, a hypothalamic signal) and short-term satiety (eg …

Insulin and leptin are hypothesized to beadiposity signals' for the long-term regulation of
body weight by the brain. Accordingly, a change in the plasma levels of leptin or insulin …