N-Dealkylation of Amines
AA Najmi, R Bischoff, HP Permentier - Molecules, 2022 - mdpi.com
N-dealkylation, the removal of an N-alkyl group from an amine, is an important chemical
transformation which provides routes for the synthesis of a wide range of pharmaceuticals …
transformation which provides routes for the synthesis of a wide range of pharmaceuticals …
Bacillus and Streptomyces spp. as hosts for production of industrially relevant enzymes
S Vojnovic, I Aleksic, T Ilic-Tomic, M Stevanovic… - Applied Microbiology …, 2024 - Springer
The application of enzymes is expanding across diverse industries due to their nontoxic and
biodegradable characteristics. Another advantage is their cost-effectiveness, reflected in …
biodegradable characteristics. Another advantage is their cost-effectiveness, reflected in …
One-pot biosynthesis of 7β-hydroxyandrost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum
YQ Zhao, YJ Liu, WT Ji, K Liu, B Gao, XY Tao… - Microbial Cell …, 2022 - Springer
Abstract Background 7β-hydroxylated steroids (7β-OHSt) possess significant activities in anti-
inflammatory and neuroprotection, and some of them have been widely used in clinics …
inflammatory and neuroprotection, and some of them have been widely used in clinics …
Synthesis of (±)‐Setigerumine I: Biosynthetic Origins of the Elusive Racemic Papaveraceae Isoxazolidine Alkaloids**
AV Serna, L Kürti, JH Siitonen - … Chemie International Edition, 2021 - Wiley Online Library
The biosynthetic origins of the structurally related racemic isoxazolidine Papaveraceae
alkaloids Setigerumine I, Dactylicapnosinine and Dactylicapnosine have remained elusive …
alkaloids Setigerumine I, Dactylicapnosinine and Dactylicapnosine have remained elusive …
Microbial P450 repertoire (P450ome) and its application feasibility in pharmaceutical industry, chemical industry, and environmental protection
Y Wang, H Pan, F Wang, C Shen - Biotechnology and …, 2024 - Wiley Online Library
Cytochrome P450s (CYPs) are heme‐thiolated enzymes that catalyze the oxidation of C‐H
bonds in a regio‐and stereo‐selective manner. CYPs are widely present in the biological …
bonds in a regio‐and stereo‐selective manner. CYPs are widely present in the biological …
The song remains the same. The lab bench dilemma of using shaken flasks in microbial biotransformation experiments
NS de Oliveira, GPL da Silva, O Furlan… - Biocatalysis and …, 2023 - Taylor & Francis
Microbial biotransformation is valuable for obtaining pharmaceutical, nutritional, and
cosmetical potential molecules. Basically, for its realization, only a parental molecule, a …
cosmetical potential molecules. Basically, for its realization, only a parental molecule, a …
New synthetic approaches enabled by electrochemistry and a nanoporous gold catalyst: for the N-dealkylation of tropanes, opiates and other drug molecules
AAN Iranag - 2022 - research.rug.nl
Carbon-nitrogen bond cleavage in the form of N-dealkylation is an important chemical
transformation which provides routes for the synthesis of a wide range of pharmaceuticals …
transformation which provides routes for the synthesis of a wide range of pharmaceuticals …