Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

The use of capping agents in the stabilization and functionalization of metallic nanoparticles for biomedical applications

S Pedroso‐Santana… - Particle & Particle …, 2023 - Wiley Online Library
The study of nanoparticles (NPs) and their application in different areas of research,
including biomedicine, is attracting the attention of researchers worldwide. Numerous …

Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay

SLY Teo, JJ Rennick, D Yuen, H Al-Wassiti… - Nature …, 2021 - nature.com
Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of
therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery …

Platinum nanozymes recover cellular ROS homeostasis in an oxidative stress-mediated disease model

M Moglianetti, E De Luca, D Pedone, R Marotta… - Nanoscale, 2016 - pubs.rsc.org
In recent years, the use of nanomaterials as biomimetic enzymes has attracted great interest.
In this work, we show the potential of biocompatible platinum nanoparticles (Pt NPs) as …

Gold nanoparticles in conjunction with nucleic acids as a modern molecular system for cellular delivery

A Graczyk, R Pawlowska, D Jedrzejczyk, A Chworos - Molecules, 2020 - mdpi.com
Development of nanotechnology has become prominent in many fields, such as medicine,
electronics, production of materials, and modern drugs. Nanomaterials and nanoparticles …

Recent uses of lipid nanoparticles, cell-penetrating and bioactive peptides for the development of brain-targeted nanomedicines against neurodegenerative disorders

Y Wu, A Angelova - Nanomaterials, 2023 - mdpi.com
The lack of effective treatments for neurodegenerative diseases (NDs) is an important
current concern. Lipid nanoparticles can deliver innovative combinations of active molecules …

Why have nanotechnologies been underutilized in the global uprising against the coronavirus pandemic?

V Uskoković - Nanomedicine, 2020 - Taylor & Francis
Prior research on nanotechnologies in diagnostics, prevention and treatment of coronavirus
infections is reviewed. Gold nanoparticles and semiconductor quantum dots in colorimetric …

Biomedical applications of the peptide decorated gold nanoparticles

A Rai, L Ferreira - Critical Reviews in Biotechnology, 2021 - Taylor & Francis
Abstract Currently, peptide-nanoparticle (NP) conjugates have been demonstrated to be
efficient and powerful tools for the treatment and the diagnosis of various diseases as well …

Intranasal delivery of recombinant AAV containing BDNF fused with HA2TAT: a potential promising therapy strategy for major depressive disorder

X Ma, P Liu, X Zhang, W Jiang, M Jia, C Wang… - Scientific reports, 2016 - nature.com
Depression is a disturbing psychiatric disease with unsatisfied therapy. Not all patients are
sensitive to anti-depressants currently in use, side-effects are unavoidable during therapy …

Tumor heterogeneity and nanoparticle-mediated tumor targeting: the importance of delivery system personalization

KL Swetha, A Roy - Drug delivery and translational research, 2018 - Springer
After the discovery of the enhanced permeability and retention effect in 1986, it was
envisioned that nanoparticle-mediated tumor-targeted delivery of chemotherapeutics would …