Experiences, whether they be learning in a classroom, a stressful event, or ingestion of a
psychoactive substance, impact the brain by modifying the activity and organization of …

Synaptic plasticity is a key component of the learning machinery in the brain. It is vital that
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …

The number and subunit composition of synaptic N-methyl-d-aspartate receptors (NMDARs)
are not static, but change in a cell-and synapse-specific manner during development and in …

Thirty years have passed since the publication of Elie Bienenstock, Leon Cooper and Paul
Munro's' Theory for the development of neuron selectivity: orientation specificity and …

Sensory experience and learning alter sensory representations in cerebral cortex. The
synaptic mechanisms underlying sensory cortical plasticity have long been sought. Recent …

Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …

The purpose of the current review is to propose a model highlighting the putative
connections between hearing loss and the phantom perception of tinnitus (tinnitus being …

NMDA-type glutamate receptors (NMDARs) mediate many forms of synaptic plasticity. These
tetrameric receptors consist of two obligatory NR1 subunits and two regulatory subunits …

Synapses are complex because they perform multiple functions, including at least six
mechanistically different forms of plasticity. Here, I comment on recent developments …

Learning, memory and brain development are associated with long-lasting modifications of
synapses that are guided by specific patterns of neuronal activity. Such modifications …