Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics

W Tang, W Fan, J Lau, L Deng, Z Shen… - Chemical Society …, 2019 - pubs.rsc.org
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …

Carbon-based nanomaterials as an emerging platform for theranostics

KD Patel, RK Singh, HW Kim - Materials Horizons, 2019 - pubs.rsc.org
Carbon-based nanomaterials include fullerenes, carbon nanotubes, graphene and its
derivatives, graphene oxide, nanodiamonds, and carbon-based quantum dots. Due to their …

Fullerenes in biology and medicine

E Castro, AH Garcia, G Zavala… - Journal of Materials …, 2017 - pubs.rsc.org
Fullerenes and related carbon based derivatives have shown a growing relevance in
biology and medicine, mainly due to the unique electronic and structural properties that …

When metal clusters meet carbon cages: endohedral clusterfullerenes

S Yang, T Wei, F Jin - Chemical society reviews, 2017 - pubs.rsc.org
Fullerenes have the characteristic of a hollow interior, and this unique feature triggers
intuitive inspiration to entrap atoms, ions or clusters inside the carbon cage in the form of …

Nanoparticle drug delivery system for glioma and its efficacy improvement strategies: a comprehensive review

J Li, J Zhao, T Tan, M Liu, Z Zeng, Y Zeng… - International Journal …, 2020 - Taylor & Francis
Gliomas are the most common tumor of the central nervous system. However, the presence
of the brain barrier blocks the effective delivery of drugs and leads to the treatment failure of …

Core–satellite polydopamine–gadolinium‐metallofullerene nanotheranostics for multimodal imaging guided combination cancer therapy

S Wang, J Lin, Z Wang, Z Zhou, R Bai, N Lu… - Advanced …, 2017 - Wiley Online Library
Integration of magnetic resonance imaging (MRI) and other imaging modalities is promising
to furnish complementary information for accurate cancer diagnosis and imaging‐guided …

Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy

L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Two Metastable Endohedral Metallofullerenes Sc2C2@C1(39656)-C82 and Sc2C2@C1(51383)-C84: Direct-C2-Insertion Products from Their Most …

YR Yao, ZC Chen, L Chen, SY Zheng… - Journal of the …, 2023 - ACS Publications
Endohedral metallofullerenes (EMFs) are sub-nano carbon materials with diverse
applications, yet their formation mechanism, particularly for metastable isomers, remains …

Fullerenes for the treatment of cancer: an emerging tool

NB Fernandes, RUK Shenoy, MK Kajampady… - … Science and Pollution …, 2022 - Springer
Cancer is a most common cause of mortality globally. Available medicines possess severe
side effects owing to their non-specific targeting. Hence, there is a need of an alternative in …

Recent development of contrast agents for magnetic resonance and multimodal imaging of glioblastoma

D Zhuang, H Zhang, G Hu, B Guo - Journal of Nanobiotechnology, 2022 - Springer
Glioblastoma (GBM) as the most common primary malignant brain tumor exhibits a high
incidence and degree of malignancy as well as poor prognosis. Due to the existence of …