Sickle cell disease (SCD) is the most common monogenic disorder in sub-Saharan Africa
(SSA). Blood transfusion to increase the oxygen carrying capacity of blood is vital in the …

Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Background: The periodic transfusion of red blood cells (RBCs) is an essential supportive
therapy for beta-thalassemia and sickle cell anemia (SCA) patients. Nevertheless, this …

BACKGROUND: Maternal alloimmunization is associated with adverse outcomes such as
hemolytic disease of the fetus and newborn. At-risk pregnant women include those with …

Introduction: La drépanocytose est un problème de santé publique. Elle entraîne des
complications aigues à type de crises vaso-occlusives, d'infections et d'hémolyse. Sa prise …

Blood transfusion in patients with sickle cell disease (SCD) is associated with the
development of antibodies against the foreign transfused red blood cell (RBC) antigens, ie …

Introduction: Red cell transfusion is an important modality in the treatment of complications
in patients with Sickle cell disease (SCD) or Thalassaemia. However, this is associated with …