Mexican plants with hypoglycaemic effect used in the treatment of diabetes

A Andrade-Cetto, M Heinrich - Journal of ethnopharmacology, 2005 - Elsevier
Diabetes mellitus is a syndrome which affects more and more people in all countries over
the world. In México, it is commonly treated with herbal extracts. Such treatment may be of …

Natural and synthetic 2H-pyran-2-ones and their versatility in organic synthesis

A Goel, VJ Ram - Tetrahedron, 2009 - Elsevier
The pyran ring system is widely present in the animal and plant kingdom and possesses
diverse pharmacological activities. Pyran is a six-membered oxygen heterocycle with two …

[HTML][HTML] Anticancer principles from medicinal Piper (胡椒Hú Jiāo) plants

YH Wang, SL Morris-Natschke, J Yang, HM Niu… - Journal of Traditional …, 2014 - Elsevier
The ethnomedical uses of Piper (胡椒Hú Jiāo) plants as anticancer agents, in vitro cytotoxic
activity of both extracts and compounds from Piper plants, and in vivo antitumor activity and …

[图书][B] Encyclopedia of dietary supplements

PM Coates, JM Betz, MR Blackman, GM Cragg… - 2010 - books.google.com
Encyclopedia of Dietary Supplements presents peer-reviewed, objective entries that
rigorously examine the most significant scientific research on basic chemical, preclinical …

Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent …

X Zi, AR Simoneau - Cancer research, 2005 - AACR
Consumption of the traditional kava preparation was reported to correlate with low and
uncustomary gender ratios (more cancer in women than men) of cancer incidences in three …

[HTML][HTML] Novel Tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis

MIM Darwish, AM Moustafa, AM Youssef, M Mansour… - Molecules, 2023 - mdpi.com
Chalcones are interesting anticancer drug candidates which have attracted much interest
due to their unique structure and their extensive biological activity. Various functional …

Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent …

YF Kuo, YZ Su, YH Tseng, SY Wang, HM Wang… - Free Radical Biology …, 2010 - Elsevier
Flavonoids synthesized from chalcone precursors in plants have been shown to possess
cytotoxic activities with therapeutic potential. We have isolated the novel chalcone …

Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages

DJ Kwon, SM Ju, GS Youn, SY Choi, J Park - Food and chemical toxicology, 2013 - Elsevier
Flavokawain A, a major constituent of chalcones derived from kava extracts, exerts various
biological activities such as anti-tumor activities. In this study, we examined the suppressive …

Plants with neurobiological activity as potential targets for drug discovery

NGM Gomes, MG Campos, JMC Órfão… - Progress in Neuro …, 2009 - Elsevier
Significant number of studies has been performed to find alternatives or treatments for
diseases of the nervous forum by identifying structures with activity at the central nervous …

[HTML][HTML] Suppression of LPS-induced inflammation by chalcone flavokawain a through activation of Nrf2/ARE-mediated antioxidant genes and inhibition of ROS/NFκB …

HL Yang, TY Yang, YV Gowrisankar, CH Liao… - … Medicine and Cellular …, 2020 - hindawi.com
Oxidative stress is an important contributing factor for inflammation. Piper methysticum, also
known as Kava-kava, is a shrub whose root extract has been consumed as a drink by the …