Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Alzheimer's disease (AD) is one of the biggest human health threats due to increases in
aging of the global population. Unfortunately, drugs for treating AD have been largely …

In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Herbal antioxidant like curcumin holds great potential to treat neurodegenerative disease
like Alzheimer's disease. However, its therapeutic potency is obstructed due to rapid …

Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …

Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In
the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein …

Deferoxamine mesylate (DFO) is an FDA-approved, hexadentate iron chelator routinely
used to alleviate systemic iron burden in thalassemia major and sickle cell patients. Iron …