Tuberculous meningitis: pathogenesis, immune responses, diagnostic challenges, and the potential of biomarker-based approaches
Tuberculous meningitis (TBM) is the most devastating form of tuberculosis (TB), causing
high mortality or disability. Clinical management of the disease is challenging due to …
high mortality or disability. Clinical management of the disease is challenging due to …
[HTML][HTML] Tuberculous meningitis in children: reducing the burden of death and disability
Tuberculous meningitis disproportionately affects young children. As the most devastating
form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity …
form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity …
[HTML][HTML] Tuberculous granuloma: emerging insights from proteomics and metabolomics
AR Sholeye, AA Williams, DT Loots… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium tuberculosis infection, which claims hundreds of thousands of lives each
year, is typically characterized by the formation of tuberculous granulomas—the …
year, is typically characterized by the formation of tuberculous granulomas—the …
Randomized clinical trial of high-dose rifampicin with or without levofloxacin versus standard of care for pediatric tuberculous meningitis: the TBM-KIDS trial
MS Paradkar, B Devaleenal D, T Mvalo… - Clinical Infectious …, 2022 - academic.oup.com
Background Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In
adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains …
adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains …
[HTML][HTML] Analysis of tuberculosis meningitis pathogenesis, diagnosis, and treatment
A Arshad, S Dayal, R Gadhe, A Mawley, K Shin… - Journal of clinical …, 2020 - mdpi.com
Tuberculosis (TB) is the most prevalent infectious disease in the world. In recent years there
has been a significant increase in the incidence of TB due to the emergence of multidrug …
has been a significant increase in the incidence of TB due to the emergence of multidrug …
Pediatric and adult meningeal, parenchymal, and spinal tuberculosis: a neuroimaging review
Neurotuberculosis is defined as a tuberculous infection of the meninges, brain parenchyma,
vessels, cranial and spinal nerves, spinal cord, skull, and spine that can occur either in a …
vessels, cranial and spinal nerves, spinal cord, skull, and spine that can occur either in a …
Treatment outcomes and risk factors of death in childhood tuberculous meningitis in Kandahar, Afghanistan: a prospective observational cohort study
BA Rahimi, N Niazi, AF Rahimi… - Transactions of The …, 2022 - academic.oup.com
Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively
documented the treatment outcomes and the risk factors for death in children with TBM from …
documented the treatment outcomes and the risk factors for death in children with TBM from …
[HTML][HTML] The Role of Oxidative Stress in TB Meningitis and Therapeutic Options
J Dawi, AS Mohan, Y Misakyan, S Affa, E Gonzalez… - Diseases, 2024 - mdpi.com
Meningitis is an inflammatory condition affecting the meninges surrounding the brain and
spinal cord. Meningitis can be triggered by various factors, including infectious agents like …
spinal cord. Meningitis can be triggered by various factors, including infectious agents like …
Advances in tuberculous meningitis diagnosis
Introduction: Tuberculous meningitis (TBM) is the most devastating form of central nervous
system tuberculosis (TB) and causes high mortality worldwide. Nonspecific clinical …
system tuberculosis (TB) and causes high mortality worldwide. Nonspecific clinical …
[HTML][HTML] Patient characteristics and predictors of mortality among children hospitalised with tuberculosis: A six-year case series study in Uganda
PM Amuge, GL Becker, RN Ssebunya, E Nalumansi… - Plos one, 2024 - journals.plos.org
Background The high case-fatality rates among children with tuberculosis (TB) are
reportedly driven by in-hospital mortality and severe forms of TB. Therefore, there is need to …
reportedly driven by in-hospital mortality and severe forms of TB. Therefore, there is need to …