Simple Summary Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed
in equine practice for a variety of painful or inflammatory conditions. This review discusses …

Pain is estimated to affect more than 20% of the global population, imposing incalculable
health and economic burdens. Effective pain management is crucial for individuals suffering …

Aromatase inhibitors (AIs) cause symptoms of musculoskeletal pain, and some mechanisms
have been proposed to explain them. However, signaling pathways downstream from kinin …

Purpose Hyperalgesia and bladder overactivity are two main symptoms of interstitial
cystitis/bladder pain syndrome (IC/BPS). Cannabinoid receptors participate in the …

Three decades ago, the first endocannabinoid, anandamide (AEA), was identified, and its
analgesic effect was recognized in humans and preclinical models. However, clinical trial …

Anandamide (AEA) is an important modulator of nociception in the spinal dorsal horn, acting
presynaptically through Cannabinoid (CB 1) and Transient receptor potential vanilloid …

Chronic pain has a high prevalence and a profound impact on patients and society, and its
treatment is a real challenge in clinical practice. Ginger is emerging as a promising …

Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel,
and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in …

Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary
medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis …

Speziell bei Migräne werden Triptane und Antikörpern gegen den Calcitonin Gene-Related
Peptide (CGRP)-Rezeptor (CGRP-Antagonisten) und CGRP-Inhibitoren, Gepante …