Nephronophthisis-related ciliopathies (NPHP-RC) are a group of inherited diseases that
affect genes encoding proteins that localize to primary cilia or centrosomes. With few …

Eukaryotic cilia and flagella are evolutionarily conserved organelles that protrude from the
cell surface. The unique location and properties of cilia allow them to function in vital …

Approximately one-third of global CO 2 fixation is performed by eukaryotic algae. Nearly all
algae enhance their carbon assimilation by operating a CO 2-concentrating mechanism …

The motile and sensory functions of cilia and flagella are indispensable for human health.
Cilia assembly requires a dedicated protein shuttle, intraflagellar transport (IFT), a …

Intraflagellar transport (IFT) is a form of motor‐dependent cargo transport that is essential for
the assembly, maintenance, and length control of cilia, which play critical roles in motility …

Intraflagellar transport (IFT) complexes, IFT-A and IFT-B, form bidirectional trains that move
along the axonemal microtubules and are essential for assembling and maintaining cilia …

Cilia and flagella are microtubule-based organelles whose assembly requires a motile
process, known as intraflagellar transport (IFT), to bring tubulin and other components to the …

Movement of cargos along microtubules plays key roles in diverse cellular processes, from
signalling to mitosis. In cilia, rapid movement of ciliary components along the microtubules to …

Intraflagellar transport (IFT) is essential for the elongation and maintenance of eukaryotic
cilia and flagella. Due to the traffic jam of multiple trains at the ciliary tip, how IFT trains are …

Specific proteins are concentrated within primary cilia, whereas others remain excluded. To
understand the mechanistic basis of entry into cilia, we developed an in vitro assay using …