Role of pharmacological active phthalazine scaffolds in medicinal chemistry

SMN Sakib - Open Science Foundation, 2023 - osf.io
Phthalazine derivatives have recently received a lot of interest in the realm of physiologically
active chemical research. Introduce this phthalazine moiety to a researcher in a new …

[PDF][PDF] Role of pharmacological active phthalazine scaffolds in medicinal chemistry: A Mini-Review

S Saha, S Duklan, A Semwal, J Kaur, M Mehra… - Eur. Chem …, 2023 - researchgate.net
The application of nitrogen-containing heterocyclic molecules in many fields, such as
pharmaceuticals, has gotten a lot of interest. Phthalazine and its oxygenated derivatives …

Huisgen 3+ n Dipolar Cycloaddition Reactions: An Accessible and Useful Tool in Modern Organic and Heterocycle Synthesis

II Mangalagiu - Molecules, 2023 - mdpi.com
Heterocycle derivatives have been reported as invaluable compounds in agriculture,
medicine, pharmacy, opto-electronics, and other fields [1–3]. Huisgen [3+ n] cycloaddition …

Fluorescent Azasteroids through Ultrasound Assisted Cycloaddition Reactions

C Moldoveanu, I Mangalagiu, G Zbancioc - Molecules, 2021 - mdpi.com
We report here the synthesis and optical spectral properties of several new azasteroid
derivatives. The formation of these compounds was explained based on the most probable …

A Green Synthetic Strategy for Pyrazolo [1, 5-a] pyrimidin-7 (4H)-one Derivatives by the Reaction of Aminopyrazoles and Symmetric/Non-symmetric Alkynes Assisted …

S Das, TRA Sangma, LB Marpna… - Periodica Polytechnica …, 2024 - pp.omikk.bme.hu
Abstract Pyrazolo [1, 5-a] pyrimidine and its derivatives possess important pharmacological
properties and hence they have drawn substantial attention as a privileged scaffold to …

Synthesis of 1-(2-Fluorophenyl) pyrazoles by 1, 3-Dipolar Cycloaddition of the Corresponding Sydnones

D Dumitrescu, S Shova, C Draghici, MM Popa… - Molecules, 2021 - mdpi.com
3-Arylsydnones bearing fluorine and bromine atoms on the benzene ring were synthesized
from N-nitroso-2-fluorophenylglycines and characterized by NMR spectroscopy. These were …

A DFT study on the mechanism and selectivity of [3+ 2] cycloaddition reactions leading to pyrole [2, 1-a] phthalazine compounds

M Lotfi, M Hamzehloueian, M Haghdadi - Theoretical Chemistry Accounts, 2021 - Springer
Abstract The mechanism of [3+ 2] cycloaddition (32CA) reactions of phthalazinium-2-
dicyanomethanide with electron-deficient and electron-rich ethylenes has been studied …

Hybrid Pyridine Bis-Anthracene-Imidazolium Salt: NMR Studies on Zn-Acetate Complexation

D Amăriucăi-Mantu, V Mangalagiu, CI Ciobanu… - Molbank, 2021 - mdpi.com
Molbank | Free Full-Text | Hybrid Pyridine Bis-Anthracene-Imidazolium Salt: NMR Studies on
Zn-Acetate Complexation Next Article in Journal 5-[4-(tert-Butyl)cyclohexylidene]-2-thioxothiazolidin-4-one …