Key Clinical Points Nonspecific Low Back Pain Nonspecific low back pain is diagnosed on
the basis of the exclusion of specific causes, usually by means of history taking and physical …

Objective To investigate the efficacy, acceptability, and safety of muscle relaxants for low
back pain. Design Systematic review and meta-analysis of randomised controlled trials …

Funding for the development of this Practice Guidance was provided by the American
Association for the Study of Liver Diseases. MV was supported by aAQ19 Patient-Centered …

Objective To investigate the effectiveness and safety of surgery compared with non-surgical
treatment for sciatica. Design Systematic review and meta-analysis. Data sources Medline …

The relationship between pain and depression is thought to be bidirectional and the
underlying neurobiology 'shared'between the two conditions. However, these claims are …

Objective The objective of the study was to determine the associations of depression and
anxiety with chronic pain among US adults. Setting Nationally representative cross …

Depression, one of the most common comorbidities with osteoarthritis (OA), affects patient
prognosis and quality of life. It also increases the overall burden of disease. This subgroup …

The Infrapatellar Fat Pad (IFP) is a fibro-adipose tissue of the knee recently reconsidered as
part of a single anatomo-functional unit (AFU) together with the synovial membrane (SM) …

Background Chronic pain is common in adults, and often has a detrimental impact upon
physical ability, well‐being, and quality of life. Previous reviews have shown that certain …

Objective To identify and descriptively compare medication recommendations among low
back pain (LBP) clinical practice guidelines (CPG). Methods We searched PubMed …