Dengue virus: epidemiology, biology, and disease aetiology
SK Roy, S Bhattacharjee - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV).
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …
Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors
K Onomoto, K Onoguchi, M Yoneyama - Cellular & molecular …, 2021 - nature.com
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are RNA sensor molecules that
play essential roles in innate antiviral immunity. Among the three RLRs encoded by the …
play essential roles in innate antiviral immunity. Among the three RLRs encoded by the …
The role of mitochondria in NLRP3 inflammasome activation
Q Liu, D Zhang, D Hu, X Zhou, Y Zhou - Molecular immunology, 2018 - Elsevier
The NLRP3 inflammasome is a multiprotein platform which is activated upon cellular
infection or stress. Its activation leads to caspase-1-dependent secretion of proinflammatory …
infection or stress. Its activation leads to caspase-1-dependent secretion of proinflammatory …
[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
Dengue virus and the host innate immune response
N Uno, TM Ross - Emerging microbes & infections, 2018 - Taylor & Francis
Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and
sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There …
sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There …
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
Immune response to dengue and Zika
A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …
are human pathogens of global significance. In particular, DENV causes the most prevalent …
[HTML][HTML] Zika virus disrupts phospho-TBK1 localization and mitosis in human neuroepithelial stem cells and radial glia
The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other
neurodevelopment defects remain poorly understood. Here, we describe the derivation and …
neurodevelopment defects remain poorly understood. Here, we describe the derivation and …
Seeking heterocyclic scaffolds as antivirals against dengue virus
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …