Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents

TJ Clough, L Jiang, KL Wong, NJ Long - Nature communications, 2019 - nature.com
Gadolinium (III) complexes have been widely utilised as magnetic resonance imaging (MRI)
contrast agents for decades. In recent years however, concerns have developed about their …

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

N Hamon, A Roux, M Beyler, JC Mulatier… - Journal of the …, 2020 - ACS Publications
In addition to the already described ligand L 4a, two pyclen-based lanthanide chelators, L
4b and L 4c, bearing two specific picolinate two-photon antennas (tailor-made for each …

[图书][B] Handbook on the physics and chemistry of rare earths: including actinides

JCG Bunzli, VK Pecharsky - 2016 - books.google.com
Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous
series of books covering all aspects of rare earth science, including chemistry, life sciences …

The use of the macrocyclic chelator DOTA in radiochemical separations

Z Baranyai, G Tircsó, F Rösch - European Journal of Inorganic …, 2020 - Wiley Online Library
Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …

Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications

L Dai, CM Jones, WTK Chan, TA Pham, X Ling… - Nature …, 2018 - nature.com
Despite established clinical utilisation, there is an increasing need for safer, more inert
gadolinium-based contrast agents, and for chelators that react rapidly with radiometals. Here …

Composed in the f-block: solution structure and function of kinetically inert lanthanide (III) complexes

LG Nielsen, AKR Junker, TJ Sørensen - Dalton transactions, 2018 - pubs.rsc.org
It has been more than 15 years since the last authoritative report on the solution structure of
lanthanide complexes made from cylcen derived polydentate ligands. The field has …

Rigidified Derivative of the Non-macrocyclic Ligand H4OCTAPA for Stable Lanthanide(III) Complexation

F Lucio-Martínez, Z Garda, B Váradi… - Inorganic …, 2022 - ACS Publications
The stability constants of lanthanide complexes with the potentially octadentate ligand CHX
OCTAPA4–, which contains a rigid 1, 2-diaminocyclohexane scaffold functionalized with two …

Design of Bifunctional Pyclen-Based Lanthanide Luminescent Bioprobes for Targeted Two-Photon Imaging

N Hamon, L Bridou, M Roux, O Maury… - The Journal of …, 2023 - ACS Publications
In the past, Lanthanide Luminescent Bioprobes (LLBs) based on pyclen-bearing π-extended
picolinate antennas were synthesized and demonstrated well-adapted optical properties for …

Isolation strategy for a novel luminescent Eu 3+-pyridine-2, 6-dicarboxylic acid complex with high compatibility and stability for light-conversion agricultural films

M Zhang, C Zhao, JQ Song, WQ He, P Zhao… - Materials Chemistry …, 2023 - pubs.rsc.org
Small organic conjugated molecule-based rare earth complexes are a kind of promising
light-conversion material used in greenhouse films to improve the crop yield. Unfortunately …