[HTML][HTML] Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?

U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …

[HTML][HTML] Therapeutic angiogenesis-based strategy for peripheral artery disease

J Han, L Luo, O Marcelina, V Kasim, S Wu - Theranostics, 2022 - ncbi.nlm.nih.gov
Peripheral artery disease (PAD) poses a great challenge to society, with a growing
prevalence in the upcoming years. Patients in the severe stages of PAD are prone to …

[HTML][HTML] Emerging roles of mesenchymal stem cell therapy in patients with critical limb ischemia

Z Shirbaghaee, M Hassani, S Heidari Keshel… - Stem Cell Research & …, 2022 - Springer
Critical limb ischemia (CLI), the terminal stage of peripheral arterial disease (PAD), is
characterized by an extremely high risk of amputation and vascular issues, resulting in …

[HTML][HTML] Mesenchymal stem cell-based therapy for non-healing wounds due to chronic limb-threatening ischemia: a review of preclinical and clinical studies

CT Huerta, FA Voza, YY Ortiz, ZJ Liu… - Frontiers in …, 2023 - frontiersin.org
Progressive peripheral arterial disease (PAD) can result in chronic limb-threatening
ischemia (CLTI) characterized by clinical complications including rest pain, gangrene and …

[HTML][HTML] Comparative analysis of mouse bone marrow and adipose tissue mesenchymal stem cells for critical limb ischemia cell therapy

P Nammian, SL Asadi-Yousefabad, S Daneshi… - Stem Cell Research & …, 2021 - Springer
Introduction Critical limb ischemia (CLI) is the most advanced form of peripheral arterial
disease (PAD) characterized by ischemic rest pain and non-healing ulcers. Currently, the …

[HTML][HTML] Therapeutic potential and molecular mechanisms of salidroside in ischemic diseases

J Han, L Luo, Y Wang, S Wu, V Kasim - Frontiers in Pharmacology, 2022 - frontiersin.org
Rhodiola is an ancient wild plant that grows in rock areas in high-altitude mountains with a
widespread habitat in Asia, Europe, and America. From empirical belief to research studies …

[HTML][HTML] Harmonised culture procedures minimise but do not eliminate mesenchymal stromal cell donor and tissue variability in a decentralised multicentre …

S Calcat-i-Cervera, E Rendra, E Scaccia… - Stem Cell Research & …, 2023 - Springer
Abstract Background Mesenchymal stromal cells (MSCs), commonly sourced from adipose
tissue, bone marrow and umbilical cord, have been widely used in many medical conditions …

[HTML][HTML] When origin matters: properties of mesenchymal stromal cells from different sources for clinical translation in kidney disease

S Calcat-i-Cervera, C Sanz-Nogués, T O'Brien - Frontiers in Medicine, 2021 - frontiersin.org
Advanced therapy medicinal products (ATMPs) offer new prospects to improve the treatment
of conditions with unmet medical needs. Kidney diseases are a current major health concern …

[HTML][HTML] Current good manufacturing practice considerations for mesenchymal stromal cells as therapeutic agents

C Sanz-Nogués, T O'Brien - Biomaterials and Biosystems, 2021 - Elsevier
Producing human mesenchymal stromal cells (MSCs) for clinical use requires adherence to
current good manufacturing practice (cGMP) standards. This is necessary for ensuring …

Application of mesenchymal stem cells in regenerative medicine: A new approach in modern medical science

F Ebrahimi, F Pirouzmand… - Biotechnology …, 2023 - Wiley Online Library
Abstract Mesenchymal Stem Cells (MSCs) are non‐hematopoietic and multipotent stem
cells, which have been considered in regenerative medicine. These cells are easily …