[HTML][HTML] Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics

H Chen, C Chen, M Spanos, G Li, R Lu, Y Bei… - … and Targeted Therapy, 2022 - nature.com
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …

The feline cardiomyopathies: 2. Hypertrophic cardiomyopathy

MD Kittleson, E Côté - Journal of feline medicine and …, 2021 - journals.sagepub.com
Practical relevance: Hypertrophic cardiomyopathy (HCM) is the most common form of feline
cardiomyopathy observed clinically and may affect up to approximately 15% of the domestic …

[HTML][HTML] Targeting the microRNA-34a as a novel therapeutic strategy for cardiovascular diseases

CC Hua, XM Liu, LR Liang, LF Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are still the main cause of morbidity and mortality
worldwide and include a group of disorders varying from vasculature, myocardium …

Mitochondrial sirtuin-3 (SIRT3) prevents doxorubicin-induced dilated cardiomyopathy by modulating protein acetylation and oxidative stress

MM Tomczyk, KG Cheung, B Xiang… - Circulation: Heart …, 2022 - Am Heart Assoc
Background: High doses of doxorubicin put cancer patients at risk for developing dilated
cardiomyopathy. Previously, we showed that doxorubicin treatment decreases SIRT3 (sirtuin …

[HTML][HTML] Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy

W Wang, L Wang, M Yang, C Wu, R Lan, W Wang… - Cell death & …, 2021 - nature.com
Mounting studies have substantiated that abrogating autophagy contributes to cardiac
hypertrophy (CH). Sirtuin 1 (SIRT1) has been reported to support autophagy and inhibit CH …

[PDF][PDF] LncRNA myocardial infarction-associated transcript (MIAT) contributed to cardiac hypertrophy by regulating TLR4 via miR-93

Y Li, J Wang, L Sun, S Zhu - Eur J Pharmacol, 2018 - academia.edu
It has been reported that lncRNA myocardial infarction-associated transcript (MIAT)
facilitated the pathological development in angiotensin II (AngII)-induced cardiac …

Function of histone methylation and acetylation modifiers in cardiac hypertrophy

J Qin, N Guo, J Tong, Z Wang - Journal of molecular and cellular cardiology, 2021 - Elsevier
Cardiac hypertrophy is an adaptive response of the heart to increased workload induced by
various physiological or pathological stimuli. It is a common pathological process in multiple …

[HTML][HTML] Restrictive cardiomyopathy: from genetics and clinical overview to animal modeling

M Chintanaphol, BO Orgil, NR Alberson… - Reviews in …, 2022 - imrpress.com
Restrictive cardiomyopathy (RCM), a potentially devastating heart muscle disorder, is
characterized by diastolic dysfunction due to abnormal muscle relaxation and myocardial …

[HTML][HTML] Effects of bergamot polyphenols on mitochondrial dysfunction and sarcoplasmic reticulum stress in diabetic cardiomyopathy

J Maiuolo, C Carresi, M Gliozzi, V Musolino, F Scarano… - Nutrients, 2021 - mdpi.com
Cardiovascular disease is the leading cause of death and disability in the Western world. In
order to safeguard the structure and the functionality of the myocardium, it is extremely …

[HTML][HTML] Alternative splicing regulator RBM20 and cardiomyopathy

T Watanabe, A Kimura, H Kuroyanagi - Frontiers in molecular …, 2018 - frontiersin.org
RBM20 is a vertebrate-specific RNA-binding protein with two zinc finger (ZnF) domains, one
RNA-recognition motif (RRM)-type RNA-binding domain and an arginine/serine (RS)-rich …