Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
Formation and function of bacterial organelles
C Greening, T Lithgow - Nature Reviews Microbiology, 2020 - nature.com
Advances in imaging technologies have revealed that many bacteria possess organelles
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
with a proteomically defined lumen and a macromolecular boundary. Some are bound by a …
Physiological limitations and opportunities in microbial metabolic engineering
J Montaño López, L Duran, JL Avalos - Nature Reviews Microbiology, 2022 - nature.com
Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …
of the transportation and chemical manufacturing sectors. The field has already developed …
[HTML][HTML] Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly
Carboxysomes are a paradigm of self-assembling proteinaceous organelles found in nature,
offering compartmentalisation of enzymes and pathways to enhance carbon fixation. In α …
offering compartmentalisation of enzymes and pathways to enhance carbon fixation. In α …
[HTML][HTML] A catalog of the diversity and ubiquity of bacterial microcompartments
Bacterial microcompartments (BMCs) are organelles that segregate segments of metabolic
pathways which are incompatible with surrounding metabolism. BMCs consist of a …
pathways which are incompatible with surrounding metabolism. BMCs consist of a …
Advances in the bacterial organelles for CO2 fixation
LN Liu - Trends in Microbiology, 2022 - cell.com
Carboxysomes are a family of bacterial microcompartments (BMCs), present in all
cyanobacteria and some proteobacteria, which encapsulate the primary CO 2-fixing …
cyanobacteria and some proteobacteria, which encapsulate the primary CO 2-fixing …
Heterologous Assembly of Pleomorphic Bacterial Microcompartment Shell Architectures Spanning the Nano‐to Microscale
Many bacteria use protein‐based organelles known as bacterial microcompartments
(BMCs) to organize and sequester sequential enzymatic reactions. Regardless of their …
(BMCs) to organize and sequester sequential enzymatic reactions. Regardless of their …
[HTML][HTML] Protein stoichiometry, structural plasticity and regulation of bacterial microcompartments
Highlights•Bacterial microcompartments (BMCs) are self-assembling organelles comprising
a protein shell that encapsulates cargo enzymes.•Unraveling the composition and …
a protein shell that encapsulates cargo enzymes.•Unraveling the composition and …
Evolutionary relationships among shell proteins of carboxysomes and metabolosomes
Highlights•Phylogenomic analysis of shell proteins uncovers supra-functional
relationships.•Alpha-carboxysome shell proteins arose independently from beta …
relationships.•Alpha-carboxysome shell proteins arose independently from beta …
Advances in the world of bacterial microcompartments
Bacterial microcompartments (MCPs) are extremely large (100–400 nm) and diverse
proteinaceous organelles that compartmentalize multistep metabolic pathways, increasing …
proteinaceous organelles that compartmentalize multistep metabolic pathways, increasing …