[HTML][HTML] Delta-9-tetrahydrocannabinol blocks bone marrow-derived macrophage differentiation through elimination of reactive oxygen species

TH Carter, CE Weyer-Nichols, JI Garcia-Sanchez… - Antioxidants, 2024 - mdpi.com
Macrophages are vital components of the immune system and serve as the first line of
defense against pathogens. Macrophage colony-stimulating factor (M-CSF) induces …

CB2 Receptor as Emerging Anti-Inflammatory Target in Duchenne Muscular Dystrophy

M Argenziano, V Pota, A Di Paola, C Tortora… - International Journal of …, 2023 - mdpi.com
Duchenne Muscular Dystrophy (DMD) is a very severe X-linked dystrophinopathy. It is due
to a mutation in the DMD gene and causes muscular degeneration in conjunction with …

Blood and urine multi-omics analysis of the impact of e-vaping, smoking, and cessation: from exposome to molecular responses

C Poussin, B Titz, Y Xiang, L Baglia, R Berg… - Scientific Reports, 2024 - nature.com
Cigarette smoking is a major preventable cause of morbidity and mortality. While quitting
smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) …

[PDF][PDF] Impact of CSE and THC on the Respiratory System Mucosa: Insights on Novel Experimental Models

A Carista, S Burgio, OM Manna, D Picone… - JOURNAL OF …, 2024 - researchgate.net
The significant role of tobacco smoking as a primary risk factor for respiratory diseases has
been extensively substantiated. In addition, cannabis use has been linked to persistent …

Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ

F da Silva Rodrigues, WR Newton, IDÁ Tassinari… - Neurochemistry …, 2024 - Elsevier
Neuroinflammation stands as a critical player in the pathogenesis of diverse neurological
disorders, with microglial cells playing a central role in orchestrating the inflammatory …

Design, characterization, and release profile of a cannabidiol (CBD)-rich polyvinyl alcohol hydrogel

S Cui, M Bahraminia, M Rouabhia, A Semlali… - Materials …, 2024 - pubs.rsc.org
Cannabidiol (CBD) has been reported to have a plethora of therapeutic opportunities in
many diseases. Current CBD delivery systems include suspension, emulsion, or …

Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study

L Renger, J Dhanani, E Milford, A Tabah, K Shekar… - Journal of Critical …, 2024 - Elsevier
Purpose To identify factors associated with cannabinoid use among patients admitted to ICU
and its impact on survival. Methods A cohort of adult patients admitted to four public …

The mechanism by which cannabidiol (CBD) suppresses TNF-α secretion involves inappropriate localization of TNF-α converting enzyme (TACE)

CM Frodella, L Liu, W Tan, SB Pruett, BLF Kaplan - Cellular Immunology, 2024 - Elsevier
Cannabidiol (CBD) is a phytocannabinoid derived from Cannabis sativa that exerts anti-
inflammatory mechanisms. CBD is being examined for its putative effects on the …

Release of delta-9-tetrahydrocannabinol from polyvinyl alcohol hydrogels and its safe interaction with human skin fibroblasts

S Cui, Z Zhang, D Rodrigue, F Béland… - Frontiers in Drug …, 2024 - frontiersin.org
This study aimed to design a THC-rich hydrogel to deliver cannabis derivatives topically. We
developed hydrogels using polyvinyl alcohol (PVA) mixed with propylene glycol (PG) …

[PDF][PDF] Development of delta-9-tetrahydrocannabinol-rich hydrogels to control tissue inflammation

S Cui - 15e JOURNÉE DE LA RECHERCHE - greb.ulaval.ca
Background: Cannabis derivatives, delta-9-tetrahydrocannabinol (THC), have shown
promising medical applications1, 2. A systematic review reported that cannabis derivatives …