Endotoxins and exotoxins are among the most potent bacterial inducers of cytokines. During
infectious processes, the production of inflammatory cytokines including tumor necrosis …

The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that
involves an uncontrolled inflammatory response by the host cells that may result in multi …

Abstract Interleukin (IL)‐18 is a pro‐inflammatory cytokine belonging to the IL‐1 family, first
identified for its interferon‐γ‐inducing properties. IL‐18 regulates both T helper (Th) 1 and …

CYTOKINES IN ACUTE AND CHRONIC INFLAMMATION Page 1 [Frontiers in Bioscience 2,
d12-26, January 1, 1997] 12 CYTOKINES IN ACUTE AND CHRONIC INFLAMMATION Carol A …

Staphylococcus aureus (S. aureus) is a Gram positive bacterium that is carried by about one
third of the general population and is responsible for common and serious diseases. These …

The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct
cell surface receptors of 55 kd (TNFRp55) and 75 kd (TNFRp75). Using gene targeting, we …

Biglycan, a small leucine-rich proteoglycan, is a ubiquitous ECM component; however, its
biological role has not been elucidated in detail. Here we show that biglycan acts in …

▪ Abstract Toxic shock syndrome (TSS) is an acute onset illness characterized by fever, rash
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …

As far back of the 1700s, it was recorded that certain infectious disease processes could be
exert beneficial therapeutic effect upon malignancy. Most prominent among the numerous …