The hallmark of Alzheimer's disease (AD) is the buildup of amyloid-β (Aβ), which is
produced when the amyloid precursor protein (APP) misfolds and deposits as neurotoxic …

The neuropathological signature of Alzheimer's disease (AD) comprises mainly amyloid
plaques, and neurofibrillary tangles, resulting in synaptic and neuronal loss. These …

Astrocytes are a type of glial cell that are involved in actively modulating synaptic plasticity,
neurotransmitter homeostasis, and neuroinflammatory responses. More importantly, they …

Alzheimer's disease (AD) affects millions of people and has limited treatment options, thus
making it a global health concern. Amyloid β (Aβ), a disrupted cholinergic system with high …

Physical activity has been demonstrated to improve cognitive function, thereby
preventing/slowing neurodegenerative diseases (NDs). Biological responses to physical …

The influence of polar, water-miscible organic solvents (POS) on protein structure, stability,
and functional activity is a subject of significant interest and complexity. This study examines …

In Alzheimers disease (AD), amyloid-beta (Aβ) peptides are produced by proteolytic
cleavage of the amyloid precursor protein (APP), which can occur during synaptic vesicle …

This article reveals the binding mechanism between glycyrrhizic acid (GA) and α-synuclein
to may provide further information for the modulation of synucleinopathies using bioactive …

Protein aggregation may lead to detrimental changes in brain and several other tissues.
Amyloids or large protein aggregates are formed in different brain areas under multiple …

Despite the current diagnostic and therapeutic approaches to bladder cancer being widely
accepted, there have been few significant advancements in this field over the past decades …