From perplexing to predictive: are we ready to forecast insect disease susceptibility in a warming world?

LV Ferguson, SA Adamo - Journal of Experimental Biology, 2023 - journals.biologists.com
Insects are critical to our ecosystems, but we do not fully understand their future in our
warming world. Rising temperatures are affecting insect physiology in myriad ways …

Altered Gut Microbiota and Immunity Defines Plasmodium vivax Survival in Anopheles stephensi

P Sharma, J Rani, C Chauhan, S Kumari… - Frontiers in …, 2020 - frontiersin.org
Blood-feeding enriched gut-microbiota boosts mosquitoes' anti-Plasmodium immunity. Here,
we ask how Plasmodium vivax alters gut-microbiota, anti-Plasmodial immunity, and impacts …

Differential expression of immunity-related genes in larval Manduca sexta tissues in response to gut and systemic infection

YM von Bredow, P Prochazkova, J Dvorak… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction The midgut epithelium functions as tissue for nutrient uptake as well as physical
barrier against pathogens. Additionally, it responds to pathogen contact by production and …

Activation of immune pathways in common bed bugs, Cimex lectularius, in response to bacterial immune challenges - a transcriptomics analysis

S Meraj, N Salcedo-Porras, C Lowenberger… - Frontiers in …, 2024 - frontiersin.org
The common bed bug, Cimex lectularius, is an urban pest of global health significance,
severely affecting the physical and mental health of humans. In contrast to most other blood …

The midgut epithelium of mosquitoes adjusts cell proliferation and endoreplication to respond to physiological challenges

ML Taracena-Agarwal, B Hixson, S Nandakumar… - BMC biology, 2024 - Springer
Background Hematophagous mosquitoes transmit many pathogens that cause human
diseases. Pathogen acquisition and transmission occur when female mosquitoes blood feed …

Immune signaling pathways in Rhodnius prolixus in the context of Trypanosoma rangeli infection: cellular and humoral immune responses and microbiota …

SB Pereira, DP Mattos, MS Gonzalez, CB Mello… - Frontiers in …, 2024 - frontiersin.org
Introduction Rhodnius prolixus is a hematophagous insect and one of the main vectors for
Trypanosoma cruzi and Trypanosoma rangeli parasites in Latin America. Gut microbiota and …

Transstadial immune activation in a mosquito: Adults that emerge from infected larvae have stronger antibacterial activity in their hemocoel yet increased susceptibility …

LD Brown, LLM Shapiro, GA Thompson… - Ecology and …, 2019 - Wiley Online Library
Larval and adult mosquitoes mount immune responses against pathogens that invade their
hemocoel. Although it has been suggested that a correlation exists between immune …

Trained Immunity in Anopheles gambiae: Antibacterial Immunity Is Enhanced by Priming via Sugar Meal Supplemented With a Single Gut Symbiotic Bacterial Strain

A Kulkarni, A Pandey, P Trainor, S Carlisle… - Frontiers in …, 2021 - frontiersin.org
Mosquitoes have evolved an effective innate immune system. The mosquito gut
accommodates various microbes, which play a crucial role in shaping the mosquito immune …

Bidirectional Microbiome-Gut-Brain-Axis Communication Influences Metabolic Switch-Associated Responses in the Mosquito Anopheles culicifacies

T Das De, P Sharma, S Tevatiya, C Chauhan, S Kumari… - Cells, 2022 - mdpi.com
The periodic ingestion of a protein-rich blood meal by adult female mosquitoes causes a
drastic metabolic change in their innate physiological status, which is referred to as a …

Activation of innate immunity selectively compromises mitochondrial complex I, proline oxidation, and flight activity in the major arbovirus vector Aedes aegypti

A Gaviraghi, ABF Barletta, TLAE Silva… - Molecular …, 2024 - Wiley Online Library
Aedes aegypti females are natural vectors of important arboviruses such as dengue, zika,
and yellow fever. Mosquitoes activate innate immune response signaling pathways upon …