Retinoic acid (RA) is a vital metabolite derived from vitamin A. RA plays a prominent role
during development, which helps in embryological advancement and cellular differentiation …

Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Targeted protein degradation (TPD), a promising therapeutic strategy in drug discovery, has
great potential to regulate the endogenous degradation of undruggable targets with small …

POU5F1 plays an important role in maintaining the cancer stem cell (CSC)-like properties of
gastric cancer (GC) cells. The impact of POU5F1 on the proliferation and metastasis of GC …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
the global pandemic and life-threatening coronavirus disease 2019 (COVID-19). Although …

Choroidal neovascularization (CNV) occurs in neovascular age-related macular
degeneration (AMD) and often leads to permanent visual impairment. Intravitreal injection of …

Abstract APR3 (Apoptosis-related protein 3) is a gene that has recently been identified to be
associated with apoptosis. The gene is located on human chromosome 2p22. 3 and …

Background Glioblastoma (GBM) is adults' most common and fatally malignant brain tumor.
The heterogeneity is the leading cause of treatment failure. However, the relationship …

Many terpenoids with isoprene unit (s) demonstrating critical biological activities have been
isolated and characterized. In this study, we have developed a robust chem‐stamp strategy …

Summary Persistentinflammatory-immunosuppressive-catabolicsyndrome (PICS) isagroupofclinicalsyndromescharacterizedb…
, immunosuppressionandtheproteincatabolic…, whichdevelopsintochroniccriticalillness …