Oncological diseases have currently reached an epidemic scale, especially in industrialized
countries. Such a situation has prompted complex studies in medicinal chemistry focused on …

Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

Microtubules are cylindrical protein polymers formed from α β-tubulin heterodimers in the
cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the …

MRSA infection is one of the alarming diseases in the current scenario. Identifying newer
molecules to treat MRSA infection is of urgent need. In the present study, we have designed …

In this work, two novel series of thiazolidin-4-one derivatives (9a–e and 10a–e) constituting
ten compounds were synthesized under batch and ultrasound irradiation. It is found that the …

Abstract Design and development of AMP‐activated protein kinase (AMPK) activator
emerged as a potential therapeutic approach for various types of cancers. In this context …

A convenient synthesis of a novel fluoroquinolone precursor, methyl 6, 7-difluoro-2-[(4-
fluorobenzyl) sulfanyl]-4-hydroxyquinoline-3-carboxylate, at a 78% yield starting from 3, 4 …

The thesis presents the synthesis and structural analysis of a series of hybrid 1H-pyrazolin/
thiazolidinones as well as of 5-ylidene derivatives of 4-phenylamino-1, 3-thiazol-2 (5H)-ones …