Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

P Intasian, K Prakinee, A Phintha, D Trisrivirat… - Chemical …, 2021 - ACS Publications
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Green and scalable fabrication of high‐performance biocatalysts using covalent organic frameworks as enzyme carriers

Y Zheng, S Zhang, J Guo, R Shi, J Yu… - Angewandte Chemie …, 2022 - Wiley Online Library
Enzyme immobilization is essential to the commercial viability of various critical large‐scale
biocatalytic processes. However, challenges remain for the immobilization systems, such as …

Development of the circular bioeconomy: Drivers and indicators

M Kardung, K Cingiz, O Costenoble, R Delahaye… - Sustainability, 2021 - mdpi.com
The EU's 2018 Bioeconomy Strategy Update and the European Green Deal recently
confirmed that the bioeconomy is high on the political agenda in Europe. Here, we propose …

Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol

J Gao, Y Li, W Yu, YJ Zhou - Nature Metabolism, 2022 - nature.com
Methanol is an ideal feedstock for biomanufacturing that can be beneficial for global carbon
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …

A comprehensive metabolic map for production of bio-based chemicals

SY Lee, HU Kim, TU Chae, JS Cho, JW Kim, JH Shin… - Nature …, 2019 - nature.com
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Metabolic engineering strategies to enable microbial utilization of C1 feedstocks

W Jiang, D Hernández Villamor, H Peng… - Nature Chemical …, 2021 - nature.com
Abstract One-carbon (C1) substrates are preferred feedstocks for the biomanufacturing
industry and have recently gained attention owing to their natural abundance, low …

Bacteria–photocatalyst sheet for sustainable carbon dioxide utilization

Q Wang, S Kalathil, C Pornrungroj, CD Sahm… - Nature Catalysis, 2022 - nature.com
The clean conversion of carbon dioxide and water to a single multicarbon product and O2
using sunlight via photocatalysis without the assistance of organic additives or electricity …

Technical photosynthesis involving CO2 electrolysis and fermentation

T Haas, R Krause, R Weber, M Demler, G Schmid - Nature Catalysis, 2018 - nature.com
Solar-powered electrochemical reduction of CO2 and H2O to syngas, followed by
fermentation, could lead to sustainable production of useful chemicals. However, due to …

Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle

P Keller, MA Reiter, P Kiefer, T Gassler… - Nature …, 2022 - nature.com
Methanol is a liquid with high energy storage capacity that holds promise as an alternative
substrate to replace sugars in the biotechnology industry. It can be produced from CO2 or …