How local groundwater induces chronic kidney disease of unknown etiology (CKDu) in Sri
Lanka is still elusive. This study aims to elucidate the impacts of Sri Lanka's local …

Advances in molecular biology are improving our understanding of the genetic causes
underlying human congenital lower urinary tract (ie, bladder and urethral) malformations …

The bladder exstrophy–epispadias complex (BEEC) is an abdominal midline malformation
comprising a spectrum of congenital genitourinary abnormalities of the abdominal wall …

CELSR3 codes for a planar cell polarity protein. We describe twelve affected individuals
from eleven independent families with bi-allelic variants in CELSR3. Affected individuals …

Background Preeclampsia (PE) poses significant diagnostic and therapeutic challenges.
This study aims to identify novel genes for potential diagnostic and therapeutic targets …

The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane
that is responsible for regulating glycine levels and contributing one-carbon units to folate …

Abstract SLC20A1/PiT1 is a sodium-dependent inorganic phosphate transporter, initially
recognized as the retroviral receptor for Gibbon Ape Leukemia Virus in humans. SNPs in …

Classic bladder exstrophy represents the most severe end of all human congenital
anomalies of the kidney and urinary tract and is associated with bladder cancer …

In recent years, exploring the potential of miRNAs as novel diagnostic, prognostic and
diagnostic markers have gained much attention. In current study, we conducted an in-depth …

Edema represents a notable outcome in fishes exposed to aquatic pollutants, yet the
underlying etiology remains inadequately understood. This investigation delves into the …