Cytokines are secreted or membrane-presented molecules that mediate broad cellular
functions, including development, differentiation, growth and survival. Accordingly, the …

Cytokines are a class of potent immunoregulatory proteins that are secreted in response to
various stimuli and act locally to regulate many aspects of human physiology and disease …

The thymus is essential for T cell development and maturation. It is extremely sensitive to
atrophy, wherein loss in cellularity of the thymus and/or disruption of the thymic architecture …

Age‐related immune dysfunctions, such as decreased T‐cell output, are closely related to
pathologies like cancers and lack of vaccine efficacy among the elderly. Engineered …

Cytokines are important regulators of immune responses, making them attractive targets for
autoimmune diseases and cancer therapeutics. Yet, the significance of cytokine …

骨髓间充质干细胞移植干预衰老猕猴胸腺结构和功能的变化 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 25|No.1|January 2021|13 骨髓间充质干细胞移植干预衰老猕猴胸腺 …

BACKGROUND: Thymus is an important central immune organ of human body, which is the
place where T cells grow, develop and mature. Thymus is the first organ of senescence in …

The global demographic is shifting at a dramatic rate. Between the years 2000 and 2050, the
number of individuals 60 years and older is expected to double accounting for more than …