Unravelling the progress and potential of drug-eluting stents and drug-coated balloons in cardiological insurgencies

Y Mukheja, A Sarkar, R Arora, K Pal, A Ahuja… - Life Sciences, 2024 - Elsevier
Aim Coronary artery disease (CAD) is the leading cause of mortality. Though percutaneous
transluminal angioplasty followed by stenting is still the default treatment of choice for …

Frontiers in artificial intelligence‐directed light‐sheet microscopy for uncovering biological phenomena and multiorgan imaging

E Zhu, YR Li, S Margolis, J Wang, K Wang, Y Zhang… - View, 2024 - Wiley Online Library
Light‐sheet fluorescence microscopy (LSFM) introduces fast scanning of biological
phenomena with deep photon penetration and minimal phototoxicity. This advancement …

Dedifferentiation and proliferation of artery endothelial cells drive coronary collateral development in mice

G Arolkar, SK Kumar, H Wang… - … , and vascular biology, 2023 - Am Heart Assoc
Background: Collateral arteries act as natural bypasses which reroute blood flow to ischemic
regions and facilitate tissue regeneration. In an injured heart, neonatal artery endothelial …

Peroxynitrite-Free Nitric Oxide-Embedded Nanoparticles Maintain Nitric Oxide Homeostasis for Effective Revascularization of Myocardial Infarcts

J Zhang, S Wang, Q Sun, J Zhang, X Shi, M Yao… - ACS …, 2024 - ACS Publications
Revascularization is crucial for treating myocardial infarction (MI). Nitric oxide (NO), at an
appropriate concentration, is recognized as an ideal and potent pro-angiogenic factor …

[HTML][HTML] Right ventricular cardiomyocyte expansion accompanies cardiac regeneration in newborn mice after large left ventricular infarcts

T Hu, MM Mohammadi, F Ebach, M Hesse, MI Kotlikoff… - JCI insight, 2024 - ncbi.nlm.nih.gov
Cauterization of the root of the left coronary artery (LCA) in the neonatal heart on postnatal
day 1 (P1) resulted in large, reproducible lesions of the left ventricle (LV), and an attendant …

Transient formation of collaterals contributes to the restoration of the arterial tree during cardiac regeneration in neonatal mice

R Sturny, L Boulgakoff, RG Kelly, L Miquerol - Journal of Molecular and …, 2024 - Elsevier
Revascularization of ischemic myocardium following cardiac damage is an important step in
cardiac regeneration. However, the mechanism of arteriogenesis has not been well …

Recasting current knowledge of human fetal circulation: the importance of computational models

D Zhang, SE Lindsey - Journal of Cardiovascular Development and …, 2023 - mdpi.com
Computational hemodynamic simulations are becoming increasingly important for
cardiovascular research and clinical practice, yet incorporating numerical simulations of …

Recent advances in quantifying the mechanobiology of cardiac development via computational modeling

AL Brown, FM Gerosa, J Wang, T Hsiai… - Current opinion in …, 2023 - Elsevier
Mechanical forces are essential for coordinating cardiac morphogenesis, but much remains
to be discovered about the interactions between mechanical forces and the …

Targeting calcineurin induces cardiomyocyte proliferation in adult mice

NT Lam, NUN Nguyen, MS Ahmed, CC Hsu… - Nature Cardiovascular …, 2022 - nature.com
The mammalian neonatal heart can regenerate for 1 week after birth, after which, the
majority of cardiomyocytes exit the cell cycle. Recent studies demonstrated that calcineurin …

[图书][B] Biomechanics of the Aorta: Modeling for Patient Care

TC Gasser, S Avril, JA Elefteriades - 2024 - books.google.com
Biomechanics of the Aorta: Modelling for Patient Care is a holistic analysis of the aorta
towards its biomechanical description. The book addresses topics such as physiology …