The acid dissociation constant is an important physicochemical parameter of a substance,
and knowledge of it is of fundamental importance in a wide range of applications and …

Explains how to perform and analyze the results of the latest physicochemical methods With
this book as their guide, readers have access to all the current information needed to …

Polyesters constitute nearly 10% of the global plastic market, but most are essentially non-
degradable under ambient conditions or in engineered environments. A range of …

The anticoagulant drug warfarin, normally administered as the racemate, can exist in
solution in potentially as many as 40 topologically distinct tautomeric forms. Only 11 of these …

Urban, hospital and pharmaceutical industry wastewater effluents are among the main
sources of antibiotics' and other antimicrobial agents' contamination in soil and water …

Purpose Assessment of the accuracy of experimental and theoretical methods of pKa
determination for acids and bases as separate classes. Methods Four literature pKa …

Antibiotics are priority contaminants of emerging concern due to their pseudo-persistence in
the environment and contribution to the development of antimicrobial resistance. In solution …

Interaction thermodynamics between warfarin, a very popular anticoagulant, and Sudlow I
binding site of human (HSA) or bovine (BSA) serum albumin have been examined in strictly …

In this paper the pH-equilibrium solubility profiles of six organic drugs are presented. The
equilibrium solubility values were determined using the saturation shake-flask and the …

The 8-hydroxyquinoline core is a privileged scaffold for drug design explored to afford novel
derivatives endowed with biological activity. Our research aimed at clarifying the antifungal …