The maturation of sleep regulatory systems during adolescence in combination with
psychosocial and societal pressures culminate in a “Perfect Storm” of short and ill-timed …

Circadian rhythm disorders have been classically associated with disorders of abnormal
timing of the sleep–wake cycle, however circadian dysfunction can play a role in a wide …

Circadian clocks drive cyclic variations in many aspects of physiology, but some daily
variations are evoked by periodic changes in the environment or sleep–wake state and …

A system of self-sustained biological clocks controls the 24-h rhythms of behavioral and
physiological processes such as the sleep–wake cycle. The circadian clock system is …

Disturbances in circadian timing can have profound effects on the quality and quantity of
sleep as well as the expression and severity of neuropsychiatric and other medical …

According to classification manuals for sleep disorders, nine disorders are directly related to
biological clock timing misalignments. Of all, delayed sleep phase disorder (DSPD) is the …

Non–24-hour sleep–wake rhythm disorder (N24SWD) is defined as a “history of insomnia,
excessive daytime sleepiness, or both, which alternate with asymptomatic episodes, owing …

Rhythm can be defined as the occurrence and recurrence of events in a regular interval of
time (Palmer, 1976). When these events involve a biological system, we consider as a …

The currently assumed aetiology for delayed sleep phase disorder (DSPD) is a delay of the
circadian system. Clinicians have sought to use bright light therapy, exogenous melatonin or …

Our objectives were to investigate the period lengths (ie, taus) of the endogenous core body
temperature rhythm and melatonin rhythm in delayed sleep-wake phase disorder patients …