As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …

The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …

Conspectus Despite tremendous research efforts in universities and pharmaceutical
companies, effective drugs are still lacking for the treatment of Alzheimer's disease (AD). The …

Aggregation of the microtubule-associated protein tau plays a major role in Alzheimer's
disease and several other neurodegenerative disorders. An exciting recent development is …

Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …

The societal cost of micronutrient deficiency (MND) or the “hidden hunger” is in millions of
dollars/year, reducing the GDP of some countries by as much as 11%. Zn is an important …

Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

Heavy metal pollution of river freshwater environments currently raises significant concerns
due to the toxic effects and the fact that heavy metal behavior is not fully understood. This …

Spinal cord injury (SCI) is accompanied by loss of Zn2+, which is an important cause of
glutamate excitotoxicity and death of local neurons as well as transplanted stem cells …

This study provides the dietary intakes of six trace elements (cadmium, chromium, copper,
manganese, selenium and zinc), generally characterized by both nutritional and …