Acute chest syndrome (ACS) is a frequent cause of acute lung disease in children with sickle
cell disease (SCD). Patients may present with ACS or may develop this complication during …

Acute chest syndrome (ACS) is a leading cause of respiratory distress and hospitalisation in
children with sickle cell disease (SCD). The aetiology is multifactorial and includes fat …

1Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, 2Lane Fox
Respiratory Unit, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust …

Acute chest syndrome (ACS) is a common complication and reason for hospital admission in
patients with sickle cell disease (SCD). It is also the most common cause of death in this …

Acute chest syndrome describes new respiratory symptoms and findings, often severe and
progressive, in a child with sickle cell disease and a new pulmonary infiltrate. It may be …

Introduction Sickle cell disease, one of the world's most prevalent Mendelian disorders, is a
chronic hemolytic anemia punctuated by acute vasoocclusive events. Both hemolysis and …

Background Globally, sickle cell disease (SCD) is one of the commonest severe monogenic
disorders, due to the inheritance of two abnormal haemoglobin (beta globin) genes. SCD …

Sickle cell disease (SCD) affects approximately 100 000 people in the US, 12 500 in the UK,
and millions worldwide. SCD is typified by painful vaso‐occlusive episodes, haemolytic …

Proper management of sickle cell anemia (SCA) begins with establishing the correct
diagnosis early in life, ideally during the newborn period. The identification of affected …

Background Sickle cell disease is an inherited autosomal recessive blood condition and is
one of the most prevalent genetic blood diseases worldwide. Acute chest syndrome is a …