The zebrafish: A fintastic model for hematopoietic development and disease
AV Gore, LM Pillay… - Wiley …, 2018 - Wiley Online Library
Hematopoiesis is a complex process with a variety of different signaling pathways
influencing every step of blood cell formation from the earliest precursors to final …
influencing every step of blood cell formation from the earliest precursors to final …
Transcriptional regulation of endothelial cell and vascular development
C Park, TM Kim, AB Malik - Circulation research, 2013 - Am Heart Assoc
The establishment and maintenance of the vascular system is critical for embryonic
development and postnatal life. Defects in endothelial cell development and vessel …
development and postnatal life. Defects in endothelial cell development and vessel …
[HTML][HTML] Retinoic acid signaling is essential for embryonic hematopoietic stem cell development
B Chanda, A Ditadi, NN Iscove, G Keller - Cell, 2013 - cell.com
Hematopoietic stem cells (HSCs) develop from a specialized subpopulation of endothelial
cells known as hemogenic endothelium (HE). Although the HE origin of HSCs is now well …
cells known as hemogenic endothelium (HE). Although the HE origin of HSCs is now well …
Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators
Advancing pluripotent stem cell technologies for modelling haematopoietic stem cell
development and blood therapies requires identifying key regulators of haematopoietic …
development and blood therapies requires identifying key regulators of haematopoietic …
A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
Haematopoietic stem cells (HSCs) are a self-renewing population of cells that continuously
replenish all blood and immune cells during the lifetime of an individual,. HSCs are used …
replenish all blood and immune cells during the lifetime of an individual,. HSCs are used …
Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm
H Kataoka, M Hayashi, R Nakagawa… - Blood, The Journal …, 2011 - ashpublications.org
Abstract Etv2 (Ets Variant 2) has been shown to be an indispensable gene for the
development of hematopoietic cells (HPCs)/endothelial cells (ECs). However, how Etv2 …
development of hematopoietic cells (HPCs)/endothelial cells (ECs). However, how Etv2 …
Signalling pathways that control vertebrate haematopoietic stem cell specification
WK Clements, D Traver - Nature Reviews Immunology, 2013 - nature.com
Haematopoietic stem cells (HSCs) are tissue-specific stem cells that replenish all mature
blood lineages during the lifetime of an individual. Clinically, HSCs form the foundation of …
blood lineages during the lifetime of an individual. Clinically, HSCs form the foundation of …
Regulation of hemogenic endothelial cell development and function
Y Wu, KK Hirschi - Annual review of physiology, 2021 - annualreviews.org
Embryonic definitive hematopoiesis generates hematopoietic stem and progenitor cells
(HSPCs) essential for establishment and maintenance of the adult blood system. This …
(HSPCs) essential for establishment and maintenance of the adult blood system. This …
Discrete Notch signaling requirements in the specification of hematopoietic stem cells
Hematopoietic stem cells (HSC s) require multiple molecular inputs for proper specification,
including activity of the Notch signaling pathway. A requirement for the Notch1 and …
including activity of the Notch signaling pathway. A requirement for the Notch1 and …
Origin of blood cells and HSC production in the embryo
G Costa, V Kouskoff, G Lacaud - Trends in immunology, 2012 - cell.com
Hematopoietic stem cells (HSCs) are capable of self-renewal and differentiation into all
blood cell types. During adult life, they reside in the bone marrow in a quiescent state. By …
blood cell types. During adult life, they reside in the bone marrow in a quiescent state. By …