Autism spectrum disorder: focus on glutamatergic neurotransmission
M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …
Modelling autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) using mice and zebrafish
Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are two
debilitating neurodevelopmental disorders. The former is associated with social impairments …
debilitating neurodevelopmental disorders. The former is associated with social impairments …
Comprehensive systematic review and meta-analysis of the association between common genetic variants and autism spectrum disorder
Y Fang, Y Cui, Z Yin, M Hou, P Guo, H Wang, N Liu… - Gene, 2023 - Elsevier
Background Autism spectrum disorder (ASD) is neurodevelopmental disorder characterized
by stereotyped behavior and deficits in communication and social interactions. To date …
by stereotyped behavior and deficits in communication and social interactions. To date …
A systematic review of common genetic variation and biological pathways in autism spectrum disorder
DA Rodriguez-Gomez, DP Garcia-Guaqueta… - BMC neuroscience, 2021 - Springer
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition
characterized by persistent deficits in social communication and interaction. Common …
characterized by persistent deficits in social communication and interaction. Common …
Neurexin gene family variants as risk factors for autism spectrum disorder
J Wang, J Gong, L Li, Y Chen, L Liu, HT Gu… - Autism …, 2018 - Wiley Online Library
Increasing evidence suggests that abnormal synaptic function leads to neuronal
developmental disorders and is an important component of the etiology of autism spectrum …
developmental disorders and is an important component of the etiology of autism spectrum …
Changes in the number and morphology of dendritic spines in the hippocampus and prefrontal cortex of the C58/J mouse model of autism
I Barón-Mendoza, E Maqueda-Martínez… - Frontiers in Cellular …, 2021 - frontiersin.org
Autism spectrum disorder (ASD) has a broad range of neurobiological characteristics,
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development
J Song, M Kang, D Park, S Park, S Lee… - Journal of …, 2021 - Soc Neuroscience
Metabotropic glutamate receptor 7 (mGlu7) is an inhibitory heterotrimeric G-protein-coupled
receptor that modulates neurotransmitter release and synaptic plasticity at presynaptic …
receptor that modulates neurotransmitter release and synaptic plasticity at presynaptic …
Metabotropic glutamate receptor 7: a new therapeutic target in neurodevelopmental disorders
NM Fisher, M Seto, CW Lindsley… - Frontiers in molecular …, 2018 - frontiersin.org
Neurodevelopmental disorders (NDDs) are characterized by a wide range of symptoms
including delayed speech, intellectual disability, motor dysfunction, social deficits, breathing …
including delayed speech, intellectual disability, motor dysfunction, social deficits, breathing …
Application of single-nucleotide polymorphisms in the diagnosis of autism spectrum disorders: a preliminary study with artificial neural networks
Autism spectrum disorder (ASD) includes different neurodevelopmental disorders
characterized by deficits in social communication, and restricted, repetitive patterns of …
characterized by deficits in social communication, and restricted, repetitive patterns of …
Retinoic acid-related orphan receptor alpha (RORA) variants are associated with autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with various
epidemiologic, genetic, epigenetic, and environmental factors being associated with it. The …
epidemiologic, genetic, epigenetic, and environmental factors being associated with it. The …