Enzymes, as nature's catalysts, speed up the very reactions that make life possible.
Hydrolytic enzymes are a particularly important enzyme class responsible for the catalytic …

Affinity chromatography is one of the powerful techniques in selective purification and
isolation of a great number of compounds. New challenges in scientific research, such as …

Self‐assembling short peptides have attracted great interest as enzyme mimics, especially if
the catalytic activity resides solely in the supramolecular structure so that it can be switched …

The development of solid-phase peptide synthesis by Bruce Merrifield paved the way for a
synthesis carried out by machines. Automated peptide synthesis is a fast and convenient …

The specific binding of RGD cyclic peptide with integrin α v β 3 attracts great research
interest for tumor-targeting drug delivery. Herein, we designed and synthesized a series of …

Bioactive hydrogels based on the self-assembly of tripeptides have attracted great interest in
recent years. In particular, the search is active for sequences that are able to mimic enzymes …

Computational modeling techniques and computer simulations have become a routine in
biological sciences and have gained great attention from researchers. Molecular dynamics …

A stochastic search algorithm is applied in order to probe the conformations of cyclic
peptides. The search is conducted in two stages. In the first stage, random conformations are …

Molecular dynamics simulations provide a sample of a molecule's conformational space.
Experiments on the μs time scale, resulting in large amounts of data, are nowadays routine …

In this report, we present the first library of tripodal synthetic receptor molecules containing
three different, temporarily N-terminal protected peptide arms capable of performing …