Strategies for targeting gene therapy in cancer cells with tumor-specific promoters
M Montaño-Samaniego, DM Bravo-Estupiñan… - Frontiers in …, 2020 - frontiersin.org
Cancer is the second cause of death worldwide, surpassed only by cardiovascular diseases,
due to the lack of early diagnosis, and high relapse rate after conventional therapies …
due to the lack of early diagnosis, and high relapse rate after conventional therapies …
Near-infrared light-triggered nano-prodrug for cancer gas therapy
Gas therapy (GT) has attracted increasing attention in recent years as a new cancer
treatment method with favorable therapeutic efficacy and reduced side effects. Several gas …
treatment method with favorable therapeutic efficacy and reduced side effects. Several gas …
Photoactivatable prodrug-backboned polymeric nanoparticles for efficient light-controlled gene delivery and synergistic treatment of platinum-resistant ovarian cancer
Combination of chemotherapy and gene therapy provides an effective strategy for cancer
treatment. However, the lack of suitable codelivery systems with efficient endo/lysosomal …
treatment. However, the lack of suitable codelivery systems with efficient endo/lysosomal …
Photochemical internalization for intracellular drug delivery. From basic mechanisms to clinical research
Photochemical internalisation (PCI) is a unique intervention which involves the release of
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …
Photodynamic therapy with smart nanomedicine
J Kim, Y Jo, K Na - Archives of pharmacal research, 2020 - Springer
For several decades, clinical demands for utilization of photodynamic therapy (PDT) have
been increasing. Notably, PDT was mainly applied for cancer therapy, and most …
been increasing. Notably, PDT was mainly applied for cancer therapy, and most …
TRAIL-based gene delivery and therapeutic strategies
H Zhong, H Wang, J Li, Y Huang - Acta Pharmacologica Sinica, 2019 - nature.com
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), also known as APO2L,
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …
A review of nanoparticle drug delivery systems responsive to endogenous breast cancer microenvironment
T Zou, W Lu, Y Mezhuev, M Lan, L Li, F Liu… - European Journal of …, 2021 - Elsevier
Breast cancer, as a malignant disease that seriously threatens women's health, urgently
needs to be researched to develop effective and safe therapeutic drugs. Nanoparticle drug …
needs to be researched to develop effective and safe therapeutic drugs. Nanoparticle drug …
Tailor‐made nanomaterials for diagnosis and therapy of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide due to
its aggressiveness and the challenge to early diagnosis and treatment. In recent decades …
its aggressiveness and the challenge to early diagnosis and treatment. In recent decades …
Mesenchymal stromal cell-based targeted therapy pancreatic cancer: Progress and challenges
Z Ma, J Hua, J Liu, B Zhang, W Wang, X Yu… - International Journal of …, 2023 - mdpi.com
Pancreatic cancer is an aggressive malignancy with high mortality rates and poor
prognoses. Despite rapid progress in the diagnosis and treatment of pancreatic cancer, the …
prognoses. Despite rapid progress in the diagnosis and treatment of pancreatic cancer, the …
Emerging role of mesenchymal stromal cells in gynecologic cancer therapy
Y Song, H Liu, S Pan, X Xiang, M Ye, X Zhu - Stem Cell Research & …, 2023 - Springer
Mesenchymal stromal cells (MSCs) show considerable promise in regenerative medicine
with superior anti-fibrotic, immunomodulatory, and angiogenic functions. More recently …
with superior anti-fibrotic, immunomodulatory, and angiogenic functions. More recently …