Free radicals are often described as chemical compounds characterized by unpaired
electrons in their outer orbital rendering them highly reactive species. In mammalians …

Aconitase, an enzyme possessing an iron–sulfur cluster that is sensitive to oxidation, is
involved in the regulation of cellular metabolism. There are two isoenzymes of aconitase …

Enzymes play key roles in fungal pathogenesis. Manipulation of enzyme expression or
activity can significantly alter the infection process, and enzyme expression profiles can be a …

Morphogenesis and stress adaptation are key attributes that allow fungal pathogens to thrive
and infect human hosts. During infection, many fungal pathogens undergo morphological …

Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

Pathogenic yeasts, either from the environment or the normal flora, have to face phagocytic
cells that constitute the first line of defence during infection. In order to evade or counteract …

Fungal pathogenicity has arisen in polyphyletic manner during evolution, yielding fungal
pathogens with diverse infection strategies and with differing degrees of evolutionary …

Aspergillus flavus is a well-known pathogenic fungus for both crops and human beings. The
acquisition of resistance to azoles by A. flavus is leading to more failures occurring in the …

Regulated synthesis of reactive oxygen species (ROS) by specific fungal NADPH oxidases
(Noxs) plays a key role in fungal cellular differentiation and development. Fungi have up to …

Fungal species display an extraordinarily diverse range of lifestyles. Nevertheless, the
survival of each species depends on its ability to sense and respond to changes in its …